| 基因名称: | SPG11 |
|---|---|
| 基因又名: | ALS5; CMT2X; KIAA1840 |
| Gene ID: | 80208 |
| 种属 | Homo sapiens |
| DNA序列编号: | NM_025137.4 |
| DNA描述 | Homo sapiens SPG11 vesicle trafficking associated, spatacsin (SPG11), transcript variant 1, mRNA |
| DNA大小: | 7772 bp |
| DNA编码区: |
atggctgcagaggaaggggtcgcgagtgctgcttccgccggcggtagctggggcaccgcg
gccatggggcgggttctaccgatgctgttggtgccagtccccgccgaggcgatggggcag
ctcggctcccgggcgcagctgcgcacacagccggaggctctggggagcctgacggctgcg
ggcagcctccaagtgctttctttgacgcctggcagccggggcgggggtcgctgctgcctg
gagggccccttctggcactttctatgggaggattctcgtaacagcagcacaccaactgaa
aagcccaaactgctcgctcttggtgaaaattatgaactgcttatctatgaatttaatttg
aaagatggaagatgtgatgcaaccattttgtatagctgtagtagggaggcattgcaaaag
ctcattgacgatcaagatatcagtatttccttattgtctttgagaatcctgtcatttcac
aataacacatcattactgttcatcaacaaatgtgtcatcctacatattatatttcctgaa
agagatgctgcaattagagtactcaactgtttcacacttcccttgcctgcacaggcagtg
gacatgattattgacacgcagctctgcagaggaattctttttgttttgagtagtttaggc
tggatctacatttttgatgttgtggatggtacatatgtagctcatgtggatttagcactt
cacaaagaagacatgtgtaatgagcagcaacaggagccagccaagatttcttcatttact
tcactgaaagtttctcaagacctcgatgttgcagtgattgtcagctcctccaactccgca
gttgctcttaacttaaatttgtatttcaggcaacacccaggacacctactgtgtgaaaga
atactagaagatcttcctattcaaggacctaagggcgtagatgaagatgatcctgttaac
tctgcctacaacatgaaactggccaagttttccttccaaattgataggtcttggaaagcc
cagctatcatcattgaatgaaacaataaagaactccaaactggaggtttcctgttgtgct
ccatggttccaggatattttgcatttggagtcacctgaatctggtaaccacagtacaagt
gtgcagagctgggccttcattccacaggacataatgcatgggcaatataatgttctacag
aaagatcatgccaagaccagtgatccaggaagatcatggaaaataatgcacatcagtgaa
caagaggaacccatagagcttaaatgtgtgtctgtgacaggattcactgcactgtttact
tgggaagtggaaaggatgggctataccattaccctctgggatttggagacccagggcatg
cagtgtttttcccttggcacaaagtgtattcctgtagacagtagtggagaccagcagctg
tgctttgttttgacagagaatggactctctctgattttgtttggtttgactcaagaagag
tttttaaacagactcatgatccatggaagtgccagcactgtggacactctttgtcatctc
aatggctggggaaggtgctcaattcccatacatgcactagaggccgggatagaaaatcgt
cagctggacacagtaaatttctttttgaagagcaaggaaaatctttttaatccatcctca
aaatcttctgtatctgatcagtttgatcacttgtcatcccatttatatttaagaaatgtg
gaagagctgataccagcattggatttactttgctcggcaattagagaaagttattctgaa
ccccaaagcaaacacttttcagaacaattgcttaatcttacactgtctttccttaacaac
caaataaaggagcttttcattcacactgaagaactagatgaacatctgcaaaaaggagtg
aacattttgactagctacattaatgaacttcgaaccttcatgataaagtttccttggaag
ctaacagatgctatagatgaatatgatgtacatgaaaatgtccccaaagtaaaggagagc
aatatatggaagaaactcagctttgaggaagttattgccagcgccattttaaacaacaaa
ataccagaggcacagactttcttcaggattgatagtcattctgctcaaaaacttgaggag
cttattggcataggcctaaatttggtctttgacaatttaaaaaagaacaatataaaggaa
gcctctgaacttttgaagaatatggggtttgatgtaaaaggccaattgctcaagatctgc
ttctatacaactaataaaaatatacgtgactttttggttgaaattttaaaagaaaaaaat
tatttttctgaaaaagagaaaagaactatagacttcgtgcatcaagttgagaagctttat
ttgggacatttccaagaaaatatgcaaatccagtcatttcccaggtactggataaaggaa
caagattttttcaagcacaagtctgttttggactcattcctgaaatatgattgtaaagat
gaatttaacaaacaggaccatagaattgtgttaaattgggctctgtggtgggatcaacta
acacaagaatccatccttctccccaggataagtccagaagaatacaaatcatattcccct
gaagccctctggagatacctcacagctcgccatgattggttaaacattatcttatggatt
ggagaatttcaaacccagcatagttatgcttcacttcagcagaacaaatggccccttctg
actgttgatgttattaaccagaatacttcctgtaacaactacatgaggaatgaaatttta
gataagctggccaggaatggggtttttttggcatctgaactggaagactttgaatgcttc
ctcctaagactgagccgtattggaggtgtaatacaggataccctccctgttcaaaactac
aagaccaaagaaggttgggatttccattctcaattcattctctattgtttggagcacagt
ctgcagcatcttctttatgtctaccttgactgttacaaacttagtcctgaaaattgtccc
tttttggaaaaaaaagagttacatgaagcacacccttggtttgaatttttagttcagtgt
cgacaagttgccagtaacttaacagatcccaaactgatcttccaggctagccttgcaaat
gctcagattttgattcccaccaatcaggccagtgtaagcagtatgctattggaaggacat
accctcctggcccttgctactacaatgtattctcctgggggtgtcagtcaggttgttcag
aatgaagaaaatgaaaactgtttgaagaaagtggatccccagctattgaagatggcatta
actccttaccccaagctaaaaactgctctcttcccacagtgcactcctcctagtgtcctg
ccatctgatattacaatctaccaccttattcagtcattatcaccctttgatcctagcaga
ttgtttggctggcagtctgctaacacactagctataggagatgcatggagtcatctccca
catttctctagccctgacctggttaataaatatgctatagtggaacgtctgaattttgct
tattatttacataatgggcggccatcatttgcatttggtacttttctggtccaggaatta
atcaagagcaagactcccaagcagctgatccagcaagtaggcaatgaagcctatgttata
gggctctcctccttccacataccttcaataggagctgcatgtgtttgtttcttagaattg
cttggccttgacagcctcaagctcagagttgatatgaaagtggccaatataattttgagc
tacaagtgcagaaatgaagatgctcagtacagctttatcagagagtctgtagccgaaaaa
ctatctaaactagctgatggtgaaaagacaaccacagaagaattgcttgttctcttagaa
gaaggtacatggaacagcattcagcaacaggaaataaagaggttatccagtgaatctagc
agccaatgggcattagtggtgcagttctgcaggctacacaatatgaaactaagcatatct
taccttagagaatgtgccaaagcaaatgattggctgcagttcattattcacagccaactc
cacaactaccacccagcagaggtgaaatcccttatccagtacttcagcccagtcattcaa
gaccacttaaggctggcttttgagaacttgccctcagtgcccacctccaaaatggacagc
gatcaagtctgcaataagtgcccccaggaacttcaaggaagcaaacaagagatgaccgat
ttatttgaaattctgctccaatgctcagaggagccagactcctggcactggcttctggtt
gaagcagtgaaacaacaggcccctatcctcagtgttctggcctcatgtctccagggtgcc
agtgccatttcttgtctctgtgtttggatcatcacttctgtggaggacaatgttgcaact
gaagcaatgggacacattcaggactcaacagaggaccatacctggaaccttgaggatctt
tcagtcatctggagaacattattaacaagacaaaagagcaaaactctcatcagaggtttc
cagcttttctttaaggattccccgttactactggtgatggagatgtatgaactgtgtatg
ttcttcaggaattataaagaagctgaagctaaacttctggagtttcagaagagccttgaa
acgcttaacacagcagccacaaaggtccaccctgtcatccctgccatgtggctggaggat
caggtgtgtttccttttgaagcttatgctacagcagtgtaagacccagtatgagctgggg
aagcttttacagctctttgttgaaagagagcatctcttctctgatggtccagatgtgaaa
aagctttgcatcctttgccagattttgaaggatacatccatagccattaatcatacaatt
attaccagctacagcattgagaatcttcagcatgaatgtagatctattttggaaagactg
cagacagatggacaattcgctttggccaggagggtagcagaattagctgagttacctgtg
gacaacttggttattaaagagataacacaggaaatgcagaccctaaaacacattgaacag
tggtcactaaaacaagcaagaattgacttctggaaaaaatgccatgagaattttaagaaa
aattcaatttcaagcaaagcagcttcttcctttttctcaacccaggcccatgtggcatgt
gagcacccaactggatggagcagcatggaggagcgccatctgctgctcaccttggcaggg
cactggcttgcccaggaggacgtggtgcccttggataagctggaggagctggagaagcag
atctggctgtgccgcatcacccagcacactcttggaagaaatcaggaggaaacagagccc
agattttctcgacagatctcaactagtggtgaactttcctttgatagtttagccagtgag
ttttccttctccaagttggctgctctgaacacatcaaaatacttagaacttaacagcctt
ccatccaaagagacatgcgagaatagattggattggaaagagcaggagtcactaaacttt
ttgattgggcgcctactggatgatggctgtgtgcatgaagcaagtagagtatgccggtat
tttcatttttataatccagatgtcgccttggtattgcactgcagagcactggcctcaggg
gaagctagtatggaggatctgcacccagagatccatgctctcctacaaagtgctgagctg
cttgaggaagaagcacccgacattcccctaaggagagtccacagcacttcaagtctggat
agtcagaagtttgtgacagtgccctccagtaatgaagtggtaactaacctggaagtgctg
acaagcaaatgcctccatgggaagaactactgtcgacaggtcctctgtctgtatgatctt
gccaaggagttgggctgttcctacacagatgttgctgctcaggatggtgaagccatgctc
cggaaaatcttggcctctcagcagcctgaccgatgcaaacgagcccaggccttcatcagc
acacagggccttaagccagatactgtggctgaactcgtggcagaagaggtgacacgggag
ctgcttacttcatcacagggaacaggacataagcagatgttcaacccaacagaggaaagc
cagacatttcttcagctgaccactctgtgtcaagaccgcacattggtaggcatgaagttg
ttggataagatttcctccgttccccatggggaactgtcttgcaccacagagctcctgatc
ctggcccatcattgcttcaccctgacgtgccacatggagggcatcatccgagtcctacag
gccgcccacatgctcacagataaccacctggcccccagtgaggagtatgggctggtggta
cggctcctcactggcattggaaggtacaacgagatgacatacatatttgatttgctgcat
aaaaagcactactttgaagtgctaatgaggaagaagttggatccgagtggtaccctgaaa
acagccctgctggactacatcaaacgctgccgtcctggagacagtgaaaagcacaatatg
attgccctgtgcttcagcatgtgccgggagattggcgagaaccacgaggcagctgcccgc
atccaactgaaattgattgagtctcagccctgggaggacagcctcaaggatgggcaccag
ctgaaacaactgctgctgaaggccctgactctgatgttggatgcagcagagagttatgcc
aaggactcctgtgtgcgacaggcccagcactgtcagcggctcaccaagttgataactctg
cagattcactttctgaacactggccagaacacaatgctcatcaacttgggccgccacaag
ctgatggactgtattctggccctacctcggttctaccaggcttctattgtggctgaggcc
tacgattttgttccagattgggctgaaattttataccagcaagtgattcttaaaggagac
tttaattacttggaagaatttaagcagcaaaggttattaaagtccagtatatttgaagag
atttccaaaaaatataaacaacatcagcctactgacatggtcatggaaaacctgaagaaa
ttactcacatattgtgaagatgtttacctgtattacaagttggcatacgaacacaagttt
tatgaaattgtaaatgtgcttctgaaggaccctcagacaggttgctgtctaaaggacatg
ctagcaggttag
|
| 蛋白序列编号: | NP_079413.3 |
| 蛋白描述: | spatacsin isoform 1 [Homo sapiens] |
| 蛋白大小: | 2443 aa |
| 蛋白序列: |
MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAA
GSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNL
KDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPE
RDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLAL
HKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCER
ILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCA
PWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISE
QEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQL
CFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENR
QLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSE
PQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWK
LTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEE
LIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKN
YFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKD
EFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWI
GEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECF
LLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCP
FLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGH
TLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVL
PSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFA
YYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLEL
LGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLE
EGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQL
HNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTD
LFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVAT
EAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCM
FFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELG
KLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERL
QTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKK
NSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQ
IWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSL
PSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASG
EASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVL
TSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFIS
TQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKL
LDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVV
RLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNM
IALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYA
KDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEA
YDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKK
LLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG
|
cDNA克隆和表达质粒购买
| 货号 | 载体 | 片段 | 标签 | 表达系统 | 价格 |
|---|---|---|---|---|---|
| NM025137-1 | pOTB7: | 全长 | 无 | cDNA克隆 | 1000 |
| NM025137-2 | pET-28a | 全长 | N-His | 大肠 | 2800 |
| NM025137-3 | pET-21b | 全长 | C-His | 大肠 | 2800 |
| NM025137-4 | pET-32a | 全长 | N-His、N-Trx | 大肠 | 2800 |
| NM025137-5 | pGEX-4T-1 | 全长 | N-GST | 大肠 | 2800 |
| NM025137-6 | pcDNA3.1(+) | 全长 | 无 | 哺乳细胞 | 2800 |
| NM025137-7 | pcDNA3.1/His A | 全长 | N-His | 哺乳细胞 | 2800 |
| NM025137-8 | pcDNA3.1/MycHisA | 全长 | C-His、C-Myc | 哺乳细胞 | 2800 |
| NM025137-9 | pCMV-Tag 2A | 全长 | N-Flag | 哺乳细胞 | 2800 |
| NM025137-10 | pCMV-Tag 4A | 全长 | C-Flag | 哺乳细胞 | 2800 |
| NM025137-11 | pCMV-HA | 全长 | N-HA | 哺乳细胞 | 2800 |
| NM025137-12 | pEGFP-C1 | 全长 | N-EGFP | 哺乳细胞 | 2800 |
| NM025137-13 | pEGFP-N1 | 全长 | C-EGFP | 哺乳细胞 | 2800 |
| NM025137-14 | p3xFlag-CMV-10 | 全长 | N-3xFlag | 哺乳细胞 | 2800 |
| NM025137-15 | p3xFlag-CMV-14 | 全长 | C-3xflag | 哺乳细胞 | 2800 |
| NM025137-16 | pLVX-Puro | 全长 | 无 | 慢病毒 | 2800 |
| NM025137-17 | pLVX-AcGFP1-N1 | 全长 | C-AcGFP | 慢病毒 | 2800 |
| NM025137-18 | pLVX-AcGFP1-C1 | 全长 | N-AcGFP | 慢病毒 | 2800 |
| NM025137-19 | pLVX-IRES-zsGreen | 全长 | 无 | 慢病毒 | 2800 |
| NM025137-20 | pFastbacI | 全长 | 无 | 昆虫细胞 | 2800 |
| NM025137-21 | pFastbac-HTB | 全长 | N-His | 昆虫细胞 | 2800 |
| NM025137-22 | pFastbac-CHis | 全长 | C-His | 昆虫细胞 | 2800 |
| NM025137-23 | pFastbac-GST | 全长 | N-GST | 昆虫细胞 | 2800 |
蛋白购买
| 基因名称 | 表达系统 | 片段 | 标签 | 产品规格 | 价格 |
|---|---|---|---|---|---|
| SPG11 | 大肠 | 全长 | N-His | 100 ug | 3500 |
| SPG11 | 哺乳 | 全长 | N-His | 100 ug | 5500 |
| SPG11 | 昆虫 | 全长 | N-His | 100 ug | 5500 |
抗体购买
| 产品名称 | 品牌 | 价格 |
|---|---|---|
| SPG11抗体/ SPG11抗体 | abcam | 询价 |
| SPG11抗体/ SPG11抗体 | CST | 询价 |
| SPG11抗体/ SPG11抗体 | Santa Cruz | 询价 |
