| 出品公司: | ATCC |
|---|---|
| 菌种名称: | ATCC36190, ATCC 36190 |
| 菌种又名: | NRRL 3655 [NRRL 11498, NRRL A-11498] |
| 菌株类型: | 刺孢小克银汉霉;刺孢小克银汉霉菌,Cunninghamella echinulata |
| 存储人: | NRRL |
| 分离来源: | |
| 产品目录号: | 36190 |
| 其他保藏库编号: | BCRC31840，ATCC 36190 ;DSM 1905 ;NRRL 11498 ;NRRL 3655 ;NRRL A-11498 |
| 培养基: |
ATCC® Medium 336: Potato dextrose agar (PDA)
|
| 生长条件: | 24 ℃ |
| 生物安全等级: | 1 |
| 模式菌株: | 否 |
| 应用: | 科研，生产，主要用于生产卡霉素衍生物马格霉素衍生物，产生亮霉素衍生物，生产尼达霉素衍生物，转化抗肿瘤药，转化倍半萜内酯costunolide，转化：抗肿瘤生物碱吖啶转化为9-羟基吖啶 |
| 菌株特点: |
ATCC 36190是刺孢小克银汉霉,Cunninghamella echinulata 。Nucleotide (GenBank) : AF043517 Cunninghamella echinulata var. echinulata major nuclease C1A
Nucleotide (GenBank) : AF109676 Cunninghamella echinulata var. echinulata minor nuclease C1B
|
| 参考文献: |
Theriault RJ. Mycarosyl macrolide antibiotics. US Patent 3,784,447 dated Jan 8 1974
Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940
Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.
Chien MM, Rosazza JP. Microbial transformations of natural antitumor agents. 9. O-Demethylation of 9-methoxyellipticine. J. Nat. Prod. 42: 643-647, 1979. PubMed: 575547
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