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基因和蛋白基本信息

基因名称: APC
基因又名: BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46
Gene ID: 324
种属 Homo sapiens
DNA序列编号: NM_001127511.3
DNA描述 Homo sapiens APC regulator of WNT signaling pathway (APC), transcript variant 1, mRNA
DNA大小: 10811 bp
DNA编码区:
atgtacgcctccctgggctcgggtccggtcgcccctttgcccgcttctgtaccaccctca
gttctcgggtcctggagcaccggcggcagcaggagctgcgtccggcaggagacgaagagc
ccgggcggcgctcgtacttctggccactgggcgagcgtctggcaggaagtacttaaacaa
ctacaaggaagtattgaagatgaagctatggcttcttctggacagattgatttattagag
cgtcttaaagagcttaacttagatagcagtaatttccctggagtaaaactgcggtcaaaa
atgtccctccgttcttatggaagccgggaaggatctgtatcaagccgttctggagagtgc
agtcctgttcctatgggttcatttccaagaagagggtttgtaaatggaagcagagaaagt
actggatatttagaagaacttgagaaagagaggtcattgcttcttgctgatcttgacaaa
gaagaaaaggaaaaagactggtattacgctcaacttcagaatctcactaaaagaatagat
agtcttcctttaactgaaaatttttccttacaaacagatatgaccagaaggcaattggaa
tatgaagcaaggcaaatcagagttgcgatggaagaacaactaggtacctgccaggatatg
gaaaaacgagcacagaggtcatctcagaacaagcatgaaaccggctcacatgatgctgag
cggcagaatgaaggtcaaggagtgggagaaatcaacatggcaacttctggtaatggtcag
ggttcaactacacgaatggaccatgaaacagccagtgttttgagttctagtagcacacac
tctgcacctcgaaggctgacaagtcatctgggaaccaaggtggaaatggtgtattcattg
ttgtcaatgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtct
agctcccaagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccag
cttttacatggcaatgacaaagactctgtattgttgggaaattcccggggcagtaaagag
gctcgggccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaag
agaggcaggcgtgaaatccgagtccttcatcttttggaacagatacgcgcttactgtgaa
acctgttgggagtggcaggaagctcatgaaccaggcatggaccaggacaaaaatccaatg
ccagctcctgttgaacatcagatctgtcctgctgtgtgtgttctaatgaaactttcattt
gatgaagagcatagacatgcaatgaatgaactagggggactacaggccattgcagaatta
ttgcaagtggactgtgaaatgtatgggcttactaatgaccactacagtattacactaaga
cgatatgctggaatggctttgacaaacttgacttttggagatgtagccaacaaggctacg
ctatgctctatgaaaggctgcatgagagcacttgtggcccaactaaaatctgaaagtgaa
gacttacagcaggttattgcgagtgttttgaggaatttgtcttggcgagcagatgtaaat
agtaaaaagacgttgcgagaagttggaagtgtgaaagcattgatggaatgtgctttagaa
gttaaaaaggaatcaaccctcaaaagcgtattgagtgccttatggaatttgtcagcacat
tgcactgagaataaagctgatatatgtgctgtagatggtgcacttgcatttttggttggc
actcttacttaccggagccagacaaacactttagccattattgaaagtggaggtgggata
ttacggaatgtgtccagcttgatagctacaaatgaggaccacaggcaaatcctaagagag
aacaactgtctacaaactttattacaacacttaaaatctcatagtttgacaatagtcagt
aatgcatgtggaactttgtggaatctctcagcaagaaatcctaaagaccaggaagcatta
tgggacatgggggcagttagcatgctcaagaacctcattcattcaaagcacaaaatgatt
gctatgggaagtgctgcagctttaaggaatctcatggcaaataggcctgcgaagtacaag
gatgccaatattatgtctcctggctcaagcttgccatctcttcatgttaggaaacaaaaa
gccctagaagcagaattagatgctcagcacttatcagaaacttttgacaatatagacaat
ttaagtcccaaggcatctcatcgtagtaagcagagacacaagcaaagtctctatggtgat
tatgtttttgacaccaatcgacatgatgataataggtcagacaattttaatactggcaac
atgactgtcctttcaccatatttgaatactacagtgttacccagctcctcttcatcaaga
ggaagcttagatagttctcgttctgaaaaagatagaagtttggagagagaacgcggaatt
ggtctaggcaactaccatccagcaacagaaaatccaggaacttcttcaaagcgaggtttg
cagatctccaccactgcagcccagattgccaaagtcatggaagaagtgtcagccattcat
acctctcaggaagacagaagttctgggtctaccactgaattacattgtgtgacagatgag
agaaatgcacttagaagaagctctgctgcccatacacattcaaacacttacaatttcact
aagtcggaaaattcaaataggacatgttctatgccttatgccaaattagaatacaagaga
tcttcaaatgatagtttaaatagtgtcagtagtagtgatggttatggtaaaagaggtcaa
atgaaaccctcgattgaatcctattctgaagatgatgaaagtaagttttgcagttatggt
caatacccagccgacctagcccataaaatacatagtgcaaatcatatggatgataatgat
ggagaactagatacaccaataaattatagtcttaaatattcagatgagcagttgaactct
ggaaggcaaagtccttcacagaatgaaagatgggcaagacccaaacacataatagaagat
gaaataaaacaaagtgagcaaagacaatcaaggaatcaaagtacaacttatcctgtttat
actgagagcactgatgataaacacctcaagttccaaccacattttggacagcaggaatgt
gtttctccatacaggtcacggggagccaatggttcagaaacaaatcgagtgggttctaat
catggaattaatcaaaatgtaagccagtctttgtgtcaagaagatgactatgaagatgat
aagcctaccaattatagtgaacgttactctgaagaagaacagcatgaagaagaagagaga
ccaacaaattatagcataaaatataatgaagagaaacgtcatgtggatcagcctattgat
tatagtttaaaatatgccacagatattccttcatcacagaaacagtcattttcattctca
aagagttcatctggacaaagcagtaaaaccgaacatatgtcttcaagcagtgagaatacg
tccacaccttcatctaatgccaagaggcagaatcagctccatccaagttctgcacagagt
agaagtggtcagcctcaaaaggctgccacttgcaaagtttcttctattaaccaagaaaca
atacagacttattgtgtagaagatactccaatatgtttttcaagatgtagttcattatca
tctttgtcatcagctgaagatgaaataggatgtaatcagacgacacaggaagcagattct
gctaataccctgcaaatagcagaaataaaagaaaagattggaactaggtcagctgaagat
cctgtgagcgaagttccagcagtgtcacagcaccctagaaccaaatccagcagactgcag
ggttctagtttatcttcagaatcagccaggcacaaagctgttgaattttcttcaggagcg
aaatctccctccaaaagtggtgctcagacacccaaaagtccacctgaacactatgttcag
gagaccccactcatgtttagcagatgtacttctgtcagttcacttgatagttttgagagt
cgttcgattgccagctccgttcagagtgaaccatgcagtggaatggtaagtggcattata
agccccagtgatcttccagatagccctggacaaaccatgccaccaagcagaagtaaaaca
cctccaccacctcctcaaacagctcaaaccaagcgagaagtacctaaaaataaagcacct
actgctgaaaagagagagagtggacctaagcaagctgcagtaaatgctgcagttcagagg
gtccaggttcttccagatgctgatactttattacattttgccacggaaagtactccagat
ggattttcttgttcatccagcctgagtgctctgagcctcgatgagccatttatacagaaa
gatgtggaattaagaataatgcctccagttcaggaaaatgacaatgggaatgaaacagaa
tcagagcagcctaaagaatcaaatgaaaaccaagagaaagaggcagaaaaaactattgat
tctgaaaaggacctattagatgattcagatgatgatgatattgaaatactagaagaatgt
attatttctgccatgccaacaaagtcatcacgtaaagcaaaaaagccagcccagactgct
tcaaaattacctccacctgtggcaaggaaaccaagtcagctgcctgtgtacaaacttcta
ccatcacaaaacaggttgcaaccccaaaagcatgttagttttacaccgggggatgatatg
ccacgggtgtattgtgttgaagggacacctataaacttttccacagctacatctctaagt
gatctaacaatcgaatcccctccaaatgagttagctgctggagaaggagttagaggaggg
gcacagtcaggtgaatttgaaaaacgagataccattcctacagaaggcagaagtacagat
gaggctcaaggaggaaaaacctcatctgtaaccatacctgaattggatgacaataaagca
gaggaaggtgatattcttgcagaatgcattaattctgctatgcccaaagggaaaagtcac
aagcctttccgtgtgaaaaagataatggaccaggtccagcaagcatctgcgtcttcttct
gcacccaacaaaaatcagttagatggtaagaaaaagaaaccaacttcaccagtaaaacct
ataccacaaaatactgaatataggacacgtgtaagaaaaaatgcagactcaaaaaataat
ttaaatgctgagagagttttctcagacaacaaagattcaaagaaacagaatttgaaaaat
aattccaaggtcttcaatgataagctcccaaataatgaagatagagtcagaggaagtttt
gcttttgattcacctcatcattacacgcctattgaaggaactccttactgtttttcacga
aatgattctttgagttctctagattttgatgatgatgatgttgacctttccagggaaaag
gctgaattaagaaaggcaaaagaaaataaggaatcagaggctaaagttaccagccacaca
gaactaacctccaaccaacaatcagctaataagacacaagctattgcaaagcagccaata
aatcgaggtcagcctaaacccatacttcagaaacaatccacttttccccagtcatccaaa
gacataccagacagaggggcagcaactgatgaaaagttacagaattttgctattgaaaat
actccggtttgcttttctcataattcctctctgagttctctcagtgacattgaccaagaa
aacaacaataaagaaaatgaacctatcaaagagactgagccccctgactcacagggagaa
ccaagtaaacctcaagcatcaggctatgctcctaaatcatttcatgttgaagatacccca
gtttgtttctcaagaaacagttctctcagttctcttagtattgactctgaagatgacctg
ttgcaggaatgtataagctccgcaatgccaaaaaagaaaaagccttcaagactcaagggt
gataatgaaaaacatagtcccagaaatatgggtggcatattaggtgaagatctgacactt
gatttgaaagatatacagagaccagattcagaacatggtctatcccctgattcagaaaat
tttgattggaaagctattcaggaaggtgcaaattccatagtaagtagtttacatcaagct
gctgctgctgcatgtttatctagacaagcttcgtctgattcagattccatcctttccctg
aaatcaggaatctctctgggatcaccatttcatcttacacctgatcaagaagaaaaaccc
tttacaagtaataaaggcccacgaattctaaaaccaggggagaaaagtacattggaaact
aaaaagatagaatctgaaagtaaaggaatcaaaggaggaaaaaaagtttataaaagtttg
attactggaaaagttcgatctaattcagaaatttcaggccaaatgaaacagccccttcaa
gcaaacatgccttcaatctctcgaggcaggacaatgattcatattccaggagttcgaaat
agctcctcaagtacaagtcctgtttctaaaaaaggcccaccccttaagactccagcctcc
aaaagccctagtgaaggtcaaacagccaccacttctcctagaggagccaagccatctgtg
aaatcagaattaagccctgttgccaggcagacatcccaaataggtgggtcaagtaaagca
ccttctagatcaggatctagagattcgaccccttcaagacctgcccagcaaccattaagt
agacctatacagtctcctggccgaaactcaatttcccctggtagaaatggaataagtcct
cctaacaaattatctcaacttccaaggacatcatcccctagtactgcttcaactaagtcc
tcaggttctggaaaaatgtcatatacatctccaggtagacagatgagccaacagaacctt
accaaacaaacaggtttatccaagaatgccagtagtattccaagaagtgagtctgcctcc
aaaggactaaatcagatgaataatggtaatggagccaataaaaaggtagaactttctaga
atgtcttcaactaaatcaagtggaagtgaatctgatagatcagaaagacctgtattagta
cgccagtcaactttcatcaaagaagctccaagcccaaccttaagaagaaaattggaggaa
tctgcttcatttgaatctctttctccatcatctagaccagcttctcccactaggtcccag
gcacaaactccagttttaagtccttcccttcctgatatgtctctatccacacattcgtct
gttcaggctggtggatggcgaaaactcccacctaatctcagtcccactatagagtataat
gatggaagaccagcaaagcgccatgatattgcacggtctcattctgaaagtccttctaga
cttccaatcaataggtcaggaacctggaaacgtgagcacagcaaacattcatcatccctt
cctcgagtaagcacttggagaagaactggaagttcatcttcaattctttctgcttcatca
gaatccagtgaaaaagcaaaaagtgaggatgaaaaacatgtgaactctatttcaggaacc
aaacaaagtaaagaaaaccaagtatccgcaaaaggaacatggagaaaaataaaagaaaat
gaattttctcccacaaatagtacttctcagaccgtttcctcaggtgctacaaatggtgct
gaatcaaagactctaatttatcaaatggcacctgctgtttctaaaacagaggatgtttgg
gtgagaattgaggactgtcccattaacaatcctagatctggaagatctcccacaggtaat
actcccccggtgattgacagtgtttcagaaaaggcaaatccaaacattaaagattcaaaa
gataatcaggcaaaacaaaatgtgggtaatggcagtgttcccatgcgtaccgtgggtttg
gaaaatcgcctgaactcctttattcaggtggatgcccctgaccaaaaaggaactgagata
aaaccaggacaaaataatcctgtccctgtatcagagactaatgaaagttctatagtggaa
cgtaccccattcagttctagcagctcaagcaaacacagttcacctagtgggactgttgct
gccagagtgactccttttaattacaacccaagccctaggaaaagcagcgcagatagcact
tcagctcggccatctcagatcccaactccagtgaataacaacacaaagaagcgagattcc
aaaactgacagcacagaatccagtggaacccaaagtcctaagcgccattctgggtcttac
cttgtgacatctgtttaa
蛋白序列编号: NP_001120983.2
蛋白描述: adenomatous polyposis coli protein isoform a [Homo sapiens]
蛋白大小: 2825 aa
蛋白序列:
MYASLGSGPVAPLPASVPPSVLGSWSTGGSRSCVRQETKSPGGARTSGHWASVWQEVLKQ
LQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGEC
SPVPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRID
SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRSSQNKHETGSHDAE
RQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSAPRRLTSHLGTKVEMVYSL
LSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKE
ARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPM
PAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLR
RYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVN
SKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVG
TLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVS
NACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYK
DANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGD
YVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGI
GLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDE
RNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQ
MKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNS
GRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQEC
VSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEER
PTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT
STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLS
SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ
GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFES
RSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAP
TAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQK
DVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEEC
IISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDM
PRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTD
EAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSS
APNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKN
NSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREK
AELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSK
DIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGE
PSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKG
DNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQA
AAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLET
KKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRN
SSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKA
PSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKS
SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSR
MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQ
AQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR
LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT
KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVW
VRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGL
ENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVA
ARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY
LVTSV

cDNA克隆和表达质粒购买

货号 载体 片段 标签 表达系统 价格
NM001127511-1 pOTB7: 全长 cDNA克隆 1000
NM001127511-2 pET-28a 全长 N-His 大肠 2800
NM001127511-3 pET-21b 全长 C-His 大肠 2800
NM001127511-4 pET-32a 全长 N-His、N-Trx 大肠 2800
NM001127511-5 pGEX-4T-1 全长 N-GST 大肠 2800
NM001127511-6 pcDNA3.1(+) 全长 哺乳细胞 2800
NM001127511-7 pcDNA3.1/His A 全长 N-His 哺乳细胞 2800
NM001127511-8 pcDNA3.1/MycHisA 全长 C-His、C-Myc 哺乳细胞 2800
NM001127511-9 pCMV-Tag 2A 全长 N-Flag 哺乳细胞 2800
NM001127511-10 pCMV-Tag 4A 全长 C-Flag 哺乳细胞 2800
NM001127511-11 pCMV-HA 全长 N-HA 哺乳细胞 2800
NM001127511-12 pEGFP-C1 全长 N-EGFP 哺乳细胞 2800
NM001127511-13 pEGFP-N1 全长 C-EGFP 哺乳细胞 2800
NM001127511-14 p3xFlag-CMV-10 全长 N-3xFlag 哺乳细胞 2800
NM001127511-15 p3xFlag-CMV-14 全长 C-3xflag 哺乳细胞 2800
NM001127511-16 pLVX-Puro 全长 慢病毒 2800
NM001127511-17 pLVX-AcGFP1-N1 全长 C-AcGFP 慢病毒 2800
NM001127511-18 pLVX-AcGFP1-C1 全长 N-AcGFP 慢病毒 2800
NM001127511-19 pLVX-IRES-zsGreen 全长 慢病毒 2800
NM001127511-20 pFastbacI 全长 昆虫细胞 2800
NM001127511-21 pFastbac-HTB 全长 N-His 昆虫细胞 2800
NM001127511-22 pFastbac-CHis 全长 C-His 昆虫细胞 2800
NM001127511-23 pFastbac-GST 全长 N-GST 昆虫细胞 2800

蛋白购买

基因名称 表达系统 片段 标签 产品规格 价格
APC 大肠 全长 N-His 100 ug 3500
APC 哺乳 全长 N-His 100 ug 5500
APC 昆虫 全长 N-His 100 ug 5500

抗体购买

产品名称 品牌 价格
APC抗体/ APC抗体 abcam 询价
APC抗体/ APC抗体 CST 询价
APC抗体/ APC抗体 Santa Cruz 询价

 

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