| 基因名称: | CDK12 |
|---|---|
| 基因又名: | CRK7; CRKR; CRKRS |
| Gene ID: | 51755 |
| 种属 | Homo sapiens |
| DNA序列编号: | NM_016507.4 |
| DNA描述 | Homo sapiens cyclin dependent kinase 12 (CDK12), transcript variant 1, mRNA |
| DNA大小: | 8287 bp |
| DNA编码区: |
atgcccaattcagagagacatgggggcaagaaggacgggagtggaggagcttctggaact
ttgcagccgtcatcgggaggcggcagctctaacagcagagagcgtcaccgcttggtatcg
aagcacaagcggcataagtccaaacactccaaagacatggggttggtgacccccgaagca
gcatccctgggcacagttatcaaacctttggtggagtatgatgatatcagctctgattcc
gacaccttctccgatgacatggccttcaaactagaccgaagggagaacgacgaacgtcgt
ggatcagatcggagcgaccgcctgcacaaacatcgtcaccaccagcacaggcgttcccgg
gacttactaaaagctaaacagaccgaaaaagaaaaaagccaagaagtctccagcaagtcg
ggatcgatgaaggaccggatatcgggaagttcaaagcgttcgaatgaggagactgatgac
tatgggaaggcgcaggtagccaaaagcagcagcaaggaatccaggtcatccaagctccac
aaggagaagaccaggaaagaacgggagctgaagtctgggcacaaagaccggagtaaaagt
catcgaaaaagggaaacacccaaaagttacaaaacagtggacagcccaaaacggagatcc
aggagcccccacaggaagtggtctgacagctccaaacaagatgatagcccctcgggagct
tcttatggccaagattatgaccttagtccctcacgatctcatacctcgagcaattatgac
tcctacaagaaaagtcctggaagtacctcgagaaggcagtcggtcagtcccccttacaag
gagccttcggcctaccagtccagcacccggtcaccgagcccctacagtaggcgacagaga
tctgtcagtccctatagcaggagacggtcgtccagctacgaaagaagtggctcttacagc
gggcgatcgcccagtccctatggtcgaaggcggtccagcagccctttcctgagcaagcgg
tctctgagtcggagtccactccccagtaggaaatccatgaagtccagaagtagaagtcct
gcatattcaagacattcatcttctcatagtaaaaagaagagatccagttcacgcagtcgt
cattccagtatctcacctgtcaggcttccacttaattccagtctgggagctgaactcagt
aggaaaaagaaggaaagagcagctgctgctgctgcagcaaagatggatggaaaggagtcc
aagggttcacctgtatttttgcctagaaaagagaacagttcagtagaggctaaggattca
ggtttggagtctaaaaagttacccagaagtgtaaaattggaaaaatctgccccagatact
gaactggtgaatgtaacacatctaaacacagaggtaaaaaattcttcagatacagggaaa
gtaaagttggatgagaactccgagaagcatcttgttaaagatttgaaagcacagggaaca
agagactctaaacccatagcactgaaagaggagattgttactccaaaggagacagaaaca
tcagaaaaggagacccctccacctcttcccacaattgcttctcccccaccccctctacca
actactacccctccacctcagacaccccctttgccacctttgcctccaataccagctctt
ccacagcaaccacctctgcctccttctcagccagcatttagtcaggttcctgcttccagt
acttcaactttgcccccttctactcactcaaagacatctgctgtgtcctctcaggcaaat
tctcagccccctgtacaggtttctgtgaagactcaagtatctgtaacagctgctattcca
cacctgaaaacttcaacgttgcctcctttgcccctcccacccttattacctggagatgat
gacatggatagtccaaaagaaactcttccttcaaaacctgtgaagaaagagaaggaacag
aggacacgtcacttactcacagaccttcctctccctccagagctccctggtggagatctg
tctcccccagactctccagaaccaaaggcaatcacaccacctcagcaaccatataaaaag
agaccaaaaatttgttgtcctcgttatggagaaagaagacaaacagaaagcgactggggg
aaacgctgtgtggacaagtttgacattattgggattattggagaaggaacctatggccaa
gtatataaagccaaggacaaagacacaggagaactagtggctctgaagaaggtgagacta
gacaatgagaaagagggcttcccaatcacagccattcgtgaaatcaaaatccttcgtcag
ttaatccaccgaagtgttgttaacatgaaggaaattgtcacagataaacaagatgcactg
gatttcaagaaggacaaaggtgccttttaccttgtatttgagtatatggaccatgactta
atgggactgctagaatctggtttggtgcacttttctgaggaccatatcaagtcgttcatg
aaacagctaatggaaggattggaatactgtcacaaaaagaatttcctgcatcgggatatt
aagtgttctaacattttgctgaataacagtgggcaaatcaaactagcagattttggactt
gctcggctctataactctgaagagagtcgcccttacacaaacaaagtcattactttgtgg
taccgacctccagaactactgctaggagaggaacgttacacaccagccatagatgtttgg
agctgtggatgtattcttggggaactattcacaaagaagcctatttttcaagccaatctg
gaactggctcagctagaactgatcagccgactttgtggtagcccttgtccagctgtgtgg
cctgatgttatcaaactgccctacttcaacaccatgaaaccgaagaagcaatatcgaagg
cgtctacgagaagaattctctttcattccttctgcagcacttgatttattggaccacatg
ctgacactagatcctagtaagcggtgcacagctgaacagaccctacagagcgacttcctt
aaagatgtcgaactcagcaaaatggctcctccagacctcccccactggcaggattgccat
gagttgtggagtaagaaacggcgacgtcagcgacaaagtggtgttgtagtcgaagagcca
cctccatccaaaacttctcgaaaagaaactacctcagggacaagtactgagcctgtgaag
aacagcagcccagcaccacctcagcctgctcctggcaaggtggagtctggggctggggat
gcaataggccttgctgacatcacacaacagctgaatcaaagtgaattggcagtgttatta
aacctgctgcagagccaaaccgacctgagcatccctcaaatggcacagctgcttaacatc
cactccaacccagagatgcagcagcagctggaagccctgaaccaatccatcagtgccctg
acggaagctacttcccagcagcaggactcagagaccatggccccagaggagtctttgaag
gaagcaccctctgccccagtgatcctgccttcagcagaacagacgacccttgaagcttca
agcacaccagctgacatgcagaatatattggcagttctcttgagtcagctgatgaaaacc
caagagccagcaggcagtctggaggaaaacaacagtgacaagaacagtgggccacagggg
ccccgaagaactcccacaatgccacaggaggaggcagcagcatgtcctcctcacattctt
ccaccagagaagaggccccctgagccccccggacctccaccgccgccacctccaccccct
ctggttgaaggcgatctttccagcgccccccaggagttgaacccagccgtgacagccgcc
ttgctgcaacttttatcccagcctgaagcagagcctcctggccacctgccacatgagcac
caggccttgagaccaatggagtactccacccgaccccgtccaaacaggacttatggaaac
actgatgggcctgaaacagggttcagtgccattgacactgatgaacgaaactctggtcca
gccttgacagaatccttggtccagaccctggtgaagaacaggaccttctcaggctctctg
agccaccttggggagtccagcagttaccagggcacagggtcagtgcagtttccaggggac
caggacctccgttttgccagggtccccttagcgttacacccggtggtcgggcaaccattc
ctgaaggctgagggaagcagcaattctgtggtacatgcagagaccaaattgcaaaactat
ggggagctggggccaggaaccactggggccagcagctcaggagcaggccttcactggggg
ggcccaactcagtcttctgcttatggaaaactctatcgggggcctacaagagtcccacca
agagggggaagagggagaggagttccttactaa
|
| 蛋白序列编号: | NP_057591.2 |
| 蛋白描述: | cyclin-dependent kinase 12 isoform 1 [Homo sapiens] |
| 蛋白大小: | 1490 aa |
| 蛋白序列: |
MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
|
cDNA克隆和表达质粒购买
| 货号 | 载体 | 片段 | 标签 | 表达系统 | 价格 |
|---|---|---|---|---|---|
| NM016507-1 | pOTB7: | 全长 | 无 | cDNA克隆 | 1000 |
| NM016507-2 | pET-28a | 全长 | N-His | 大肠 | 2800 |
| NM016507-3 | pET-21b | 全长 | C-His | 大肠 | 2800 |
| NM016507-4 | pET-32a | 全长 | N-His、N-Trx | 大肠 | 2800 |
| NM016507-5 | pGEX-4T-1 | 全长 | N-GST | 大肠 | 2800 |
| NM016507-6 | pcDNA3.1(+) | 全长 | 无 | 哺乳细胞 | 2800 |
| NM016507-7 | pcDNA3.1/His A | 全长 | N-His | 哺乳细胞 | 2800 |
| NM016507-8 | pcDNA3.1/MycHisA | 全长 | C-His、C-Myc | 哺乳细胞 | 2800 |
| NM016507-9 | pCMV-Tag 2A | 全长 | N-Flag | 哺乳细胞 | 2800 |
| NM016507-10 | pCMV-Tag 4A | 全长 | C-Flag | 哺乳细胞 | 2800 |
| NM016507-11 | pCMV-HA | 全长 | N-HA | 哺乳细胞 | 2800 |
| NM016507-12 | pEGFP-C1 | 全长 | N-EGFP | 哺乳细胞 | 2800 |
| NM016507-13 | pEGFP-N1 | 全长 | C-EGFP | 哺乳细胞 | 2800 |
| NM016507-14 | p3xFlag-CMV-10 | 全长 | N-3xFlag | 哺乳细胞 | 2800 |
| NM016507-15 | p3xFlag-CMV-14 | 全长 | C-3xflag | 哺乳细胞 | 2800 |
| NM016507-16 | pLVX-Puro | 全长 | 无 | 慢病毒 | 2800 |
| NM016507-17 | pLVX-AcGFP1-N1 | 全长 | C-AcGFP | 慢病毒 | 2800 |
| NM016507-18 | pLVX-AcGFP1-C1 | 全长 | N-AcGFP | 慢病毒 | 2800 |
| NM016507-19 | pLVX-IRES-zsGreen | 全长 | 无 | 慢病毒 | 2800 |
| NM016507-20 | pFastbacI | 全长 | 无 | 昆虫细胞 | 2800 |
| NM016507-21 | pFastbac-HTB | 全长 | N-His | 昆虫细胞 | 2800 |
| NM016507-22 | pFastbac-CHis | 全长 | C-His | 昆虫细胞 | 2800 |
| NM016507-23 | pFastbac-GST | 全长 | N-GST | 昆虫细胞 | 2800 |
蛋白购买
| 基因名称 | 表达系统 | 片段 | 标签 | 产品规格 | 价格 |
|---|---|---|---|---|---|
| CDK12 | 大肠 | 全长 | N-His | 100 ug | 3500 |
| CDK12 | 哺乳 | 全长 | N-His | 100 ug | 5500 |
| CDK12 | 昆虫 | 全长 | N-His | 100 ug | 5500 |
抗体购买
| 产品名称 | 品牌 | 价格 |
|---|---|---|
| CDK12抗体/ CDK12抗体 | abcam | 询价 |
| CDK12抗体/ CDK12抗体 | CST | 询价 |
| CDK12抗体/ CDK12抗体 | Santa Cruz | 询价 |
