DOCK1基因DOCK1蛋白

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基因和蛋白基本信息

基因名称: DOCK1
基因又名: ced5; DOCK180
Gene ID: 1793
种属 Homo sapiens
DNA序列编号: NM_001290223.2
DNA描述 Homo sapiens dedicator of cytokinesis 1 (DOCK1), transcript variant 1, mRNA
DNA大小: 6840 bp
DNA编码区:
atgacgcgctgggtgcccaccaagcgcgaggagaagtacggcgtggctttttataactat
gatgccagaggagcggatgaactttctttacagatcggagacactgtgcacatcttagaa
acatatgaagggtggtaccgaggttacacgttacgaaaaaagtctaagaagggtatattt
cctgcttcatatattcatcttaaagaagcgatagttgaaggaaaagggcaacatgaaaca
gtcatcccgggtgacctccccctcatccaggaagtcaccacgacactccgagagtggtcc
accatctggaggcagctctacgtgcaagataacagggagatgtttcgaagtgtgcggcac
atgatctatgaccttattgaatggcgatcacaaattctttctggaactctgcctcaggat
gaactcaaagaactgaagaagaaggtcacagccaaaattgattatggaaacagaattcta
gatttggacctggtggttagagatgaagatgggaatattttggatccagaattaactagc
acgattagtctcttcagagctcatgaaatagcttctaaacaagtggaggaaaggttacaa
gaggaaaaatctcaaaagcagaacatagatattaacagacaagccaagtttgctgcaacc
ccttctctggccttgtttgtgaacctcaaaaatgtggtttgtaaaataggagaagatgct
gaagtcctcatgtctctatatgaccctgtggagtccaaattcatcagtgagaactacctg
gttcgctggtccagttcaggattacctaaagacatagacagattacataatttgcgagcc
gtgtttactgacctcggaagcaaagacctgaaaagggagaaaatcagttttgtctgtcag
attgttcgcgtgggtcgcatggagctgagggacaacaacaccaggaaactgacctcgggg
ttgcggcgaccttttggagtggctgtgatggatgtaacagatataataaatggaaaagta
gatgatgaagataagcagcatttcattccctttcagccgctcgcgttggacgacgccatt
cgacacaagccgctgaacatgtcatcccgtttttcacccagggtggcaggggagaatgac
ttccttcagactgttataaacaaagtcatcgctgccaaagaagtcaaccacaaggggcag
ggtttgtgggtaacattgaaattacttcctggagatatccatcagatccgaaaagagttt
ccgcatttagtggacaggaccacagctgtggctcgaaaaacagggtttccggagataatc
atgcctggtgatgttcgaaatgatatctatgtaacattagttcaaggagattttgataaa
ggaagcaaaacaacagcgaagaacgtggaggtcacggtgtctgtgtacgatgaggatggg
aaacgattagagcatgtgattttcccgggtgctggtgatgaagcgatttcagagtacaaa
tctgtgatttactaccaagtaaagcagccacgctggtttgagactgttaaggtggccatt
cccatcgaggacgttaaccgcagtcaccttcggtttaccttccgccacaggtcatcacag
gactctaaggataaatctgagaaaatatttgcactagcatttgtcaagctgatgagatac
gatggtaccaccctgcgagacggagagcacgatcttatcgtctataaggccgaagcaaag
aagctggaagatgctgccacgtacttgagtctgccctccacgaaggcagagttggaagaa
aagggccactcggccaccggcaagagcatgcagagccttgggagctgcaccattagcaag
gactccttccagatctccacgctcgtgtgctccaccaaactgactcagaacgtggacctt
ctggggctcttgaaatggcgctccaacaccagcctgctgcagcagaacttgaggcagctg
atgaaagtcgatggtggtgaagtagtgaagtttcttcaggacacgttggatgccctcttc
aacatcatgatggagaactcagagagtgagacttttgacacgttagtctttgatgctctg
gtatttatcattggactgattgctgatagaaaatttcagcattttaatcctgttttggaa
acttacattaagaaacactttagtgcaacgttagcctacacgaagttgacaaaagtgttg
aagaactacgtggacggtgctgagaagccgggagtaaatgagcagctgtacaaagccatg
aaagcgctagaatccatcttcaagttcatcgtgcgctccaggatcctgttcaatcaactg
tatgaaaacaagggagaggctgacttcgtggaatctttgctgcagctcttcaggtccatc
aatgacatgatgagcagcatgtcagaccagaccgtccgggtgaagggggcagcactgaaa
tacttaccaacgatcgtcaacgatgtgaaattggtgtttgatcccaaagagctcagcaaa
atgtttactgaattcatcctcaatgttcccatgggcttgctgaccatccagaaactctac
tgcttgatcgaaatcgtccacagtgacctcttcacacagcatgactgcagagagatcctg
cttcccatgatgaccgatcagctcaagtaccatctggagagacaggaggacctggaggcc
tgctgtcagctgctcagccacatcctggaggtgctgtacaggaaggacgtggggccaacc
cagaggcacgtccagattatcatggagaaacttctccggaccgtgaaccgaaccgtcatt
tccatgggacgagattctgaactcattggaaacttcgtggcttgcatgacagctatttta
cgacaaatggaagattaccattatgcccacttgatcaagacttttgggaaaatgaggact
gatgtggtagatttcctaatggaaacattcatcatgtttaagaacctcattggaaagaac
gtttaccccttcgactgggtgatcatgaacatggtgcaaaataaagtcttcctgcgagca
attaatcagtatgcagatatgctgaacaaaaaatttctggatcaagccaactttgagcta
cagctgtggaacaactactttcacctggctgttgctttccttactcaagagtccctgcaa
ctggagaatttttcaagtgccaagagagccaaaatccttaacaagtacggagatatgagg
agacagattggctttgaaatcagagacatgtggtacaaccttggtcaacacaagataaag
ttcattccagaaatggtgggcccaatattagaaatgacattaattcccgagacggagctg
cgcaaagccaccatccccatcttctttgatatgatgcagtgtgaattccattcgacccga
agcttccaaatgtttgaaaatgagatcatcaccaagctggatcatgaagtcgaaggaggc
agaggagacgaacagtacaaagtgttatttgataaaatccttctggaacactgcaggaag
cacaaatacctcgccaaaacaggagaaacttttgtaaaactcgttgtgcgcttaatggaa
aggcttttggattatagaaccatcatgcacgacgagaacaaagaaaaccgcatgagctgc
accgtcaatgtgctgaatttctacaaagaaattgaaagagaagaaatgtatataaggtat
ttgtacaagctctgtgacctgcacaaggagtgtgataactacaccgaagcggcttacacc
ttgcttctccatgcaaagcttcttaagtggtcggaggatgtgtgtgtggcccacctcacc
cagcgggacgggtaccaggccaccacgcagggacagctgaaggagcagctctaccaggaa
atcatccactacttcgacaaaggcaagatgtgggaggaggccattgccttgggcaaggag
ctagccgagcagtatgagaacgaaatgtttgattatgagcaactcagcgaattgctgaaa
aaacaggctcagttttatgaaaacatcgtcaaagtgatcaggcccaagcctgactatttt
gctgttggctactacggacaagggttccccacattcctgcggggaaaagttttcatttac
cgagggaaagagtatgagcgccgggaagattttgaggctcggctcttaactcagtttcca
aacgccgagaaaatgaagacaacatctccaccaggcgacgatattaaaaactctcctggc
cagtatattcagtgcttcacagtgaagcccaaactcgatctgcctcctaagtttcacagg
ccagtgtcagagcagattgtaagtttttacagggtgaacgaggtccagcgatttgaatat
tctcggccaatccggaagggagagaaaaacccagacaatgaatttgcgaatatgtggatc
gagagaaccatatatacaactgcatataaattacctggaattttaaggtggtttgaggtc
aagtctgttttcatggtggaaatcagccccctggagaatgccattgagaccatgcagctg
acgaacgacaagatcaacagcatggtgcagcagcacctggatgaccccagcctgcccatc
aacccgctctccatgctcctgaacggcatcgtggacccagctgtcatggggggcttcgca
aactacgaaaaggccttctttacagaccggtacctgcaggagcaccctgaggcccatgaa
aagatcgagaagctcaaggacctgattgcttggcagattccttttctggccgaagggatc
agaatccatggagacaaagtcacggaggcactgaggccgttccacgagaggatggaggcc
tgtttcaaacagctgaaggaaaaggtggagaaagagtacggcgtccgaatcatgccctca
agtctggatgatagaagaggcagccgcccccggtccatggtgcggtccttcacgatgcct
tcctcatcccgccctctgtctgtggcctctgtctcttccctctcatcggacagcacccct
tccagaccaggctccgacgggtttgccctggagcctctcctgccaaagaaaatgcactcc
aggtcccaggacaagctggacaaggatgacctggagaaggagaagaaggacaagaagaag
gaaaaaaggaacagcaaacatcaagagatatttgagaaagaatttaaacccaccgacatt
tccctgcagcagtctgaggctgtgatcctttcggaaacgataagtcccctgcggccccag
agaccgaagagccaggtgatgaacgtcattggaagcgaaaggcgcttctcggtgtccccc
tcgtcaccgtcctcccagcaaacaccccctccagttacaccaagggccaagctcagcttc
agcatgcagtcgagcttggagctgaacggcatgacgggggcggacgtggccgatgtccca
ccccctctgcctctcaaaggcagcgtggcagattacgggaatttgatggaaaaccaggac
ttgctgggctcgccaacacctccacctccccctccacaccagaggcatctgccacctcca
ctgcccagcaaaactccgcctcctccccctccaaagacaactcgcaagcaggcatcggtg
gactccgggatcgtgcagtga
蛋白序列编号: NP_001277152.2
蛋白描述: dedicator of cytokinesis protein 1 isoform 1 [Homo sapiens]
蛋白大小: 1886 aa
蛋白序列:
MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF
PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH
MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS
TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA
EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ
IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPLALDDAI
RHKPLNMSSRFSPRVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDG
KRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ
DSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQL
MKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLE
TYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL
YENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSK
MFTEFILNVPMGLLTIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEA
CCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRA
INQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMR
RQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLME
RLLDYRTIMHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYT
LLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIY
RGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHR
PVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFA
NYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEA
CFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDI
SLQQSEAVILSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSF
SMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPP
LPSKTPPPPPPKTTRKQASVDSGIVQ

cDNA克隆和表达质粒购买

货号 载体 片段 标签 表达系统 价格
NM001290223-1 pOTB7: 全长 cDNA克隆 1000
NM001290223-2 pET-28a 全长 N-His 大肠 2800
NM001290223-3 pET-21b 全长 C-His 大肠 2800
NM001290223-4 pET-32a 全长 N-His、N-Trx 大肠 2800
NM001290223-5 pGEX-4T-1 全长 N-GST 大肠 2800
NM001290223-6 pcDNA3.1(+) 全长 哺乳细胞 2800
NM001290223-7 pcDNA3.1/His A 全长 N-His 哺乳细胞 2800
NM001290223-8 pcDNA3.1/MycHisA 全长 C-His、C-Myc 哺乳细胞 2800
NM001290223-9 pCMV-Tag 2A 全长 N-Flag 哺乳细胞 2800
NM001290223-10 pCMV-Tag 4A 全长 C-Flag 哺乳细胞 2800
NM001290223-11 pCMV-HA 全长 N-HA 哺乳细胞 2800
NM001290223-12 pEGFP-C1 全长 N-EGFP 哺乳细胞 2800
NM001290223-13 pEGFP-N1 全长 C-EGFP 哺乳细胞 2800
NM001290223-14 p3xFlag-CMV-10 全长 N-3xFlag 哺乳细胞 2800
NM001290223-15 p3xFlag-CMV-14 全长 C-3xflag 哺乳细胞 2800
NM001290223-16 pLVX-Puro 全长 慢病毒 2800
NM001290223-17 pLVX-AcGFP1-N1 全长 C-AcGFP 慢病毒 2800
NM001290223-18 pLVX-AcGFP1-C1 全长 N-AcGFP 慢病毒 2800
NM001290223-19 pLVX-IRES-zsGreen 全长 慢病毒 2800
NM001290223-20 pFastbacI 全长 昆虫细胞 2800
NM001290223-21 pFastbac-HTB 全长 N-His 昆虫细胞 2800
NM001290223-22 pFastbac-CHis 全长 C-His 昆虫细胞 2800
NM001290223-23 pFastbac-GST 全长 N-GST 昆虫细胞 2800

蛋白购买

基因名称 表达系统 片段 标签 产品规格 价格
DOCK1 大肠 全长 N-His 100 ug 3500
DOCK1 哺乳 全长 N-His 100 ug 5500
DOCK1 昆虫 全长 N-His 100 ug 5500

抗体购买

产品名称 品牌 价格
DOCK1抗体/ DOCK1抗体 abcam 询价
DOCK1抗体/ DOCK1抗体 CST 询价
DOCK1抗体/ DOCK1抗体 Santa Cruz 询价

 

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