DOCK8基因DOCK8蛋白

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基因和蛋白基本信息

基因名称: DOCK8
基因又名: HEL-205; MRD2; ZIR8
Gene ID: 81704
种属 Homo sapiens
DNA序列编号: NM_203447.4
DNA描述 Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 1, mRNA
DNA大小: 7448 bp
DNA编码区:
atggccactctgccgagcgcagagcgccgcgcgttcgcgctcaagatcaacaggtattct
tcagcggaaataaggaaacagtttactctcccaccaaaccttggccagtaccatcgacag
agcataagtacctctggcttcccctctcttcaactacctcagttttatgaccctgtggag
ccagtggactttgaaggacttctgatgacacacctgaacagcctggatgtgcagcttgcc
caggagctcggggacttcactgatgacgacttggacgtggtgttcacgccaaaggaatgt
aggactttgcagccctctttgccggaggaaggggttgaactggaccctcatgtcagggac
tgtgttcagacctacatccgtgagtggctaatcgtgaaccggaaaaaccaaggaagtcca
gaaatctgtggctttaaaaagactggatctcgaaaagattttcacaagacgcttccgaaa
cagacgtttgagtcggaaaccttggagtgcagtgaacccgctgctcaggcaggcccccgc
cacttaaacgtgctgtgcgacgtgtctgggaaaggccccgtcactgcctgtgactttgac
ctccgcagcctgcagcctgacaagcggctagaaaacctcctgcagcaagtgagtgccgag
gactttgagaagcagaacgaggaggcccggaggaccaataggcaggccgagctctttgcc
ctttacccatcagtggacgaggaggatgctgtggaaatacgtccagtaccagaatgtccc
aaggaacacctgggcaacagaatattggtcaagttgctgaccttgaagttcgagattgaa
attgagcccctgtttgccagcattgccctctacgatgttaaagaaaggaaaaagatctca
gaaaattttcactgtgacctgaactctgaccagttcaaaggatttctgcgagctcacacg
ccttcagtggccgcatcaagtcaggcgagatctgcagtcttctcagtcacctacccgtcc
tcagacatctacctggtagtcaagattgaaaaagtcctgcagcagggagagattggagac
tgtgcagagccctacacggttatcaaagaaagtgatggtggaaagagtaaagaaaagatt
gaaaaactaaaactccaagctgaatccttctgccagcgtttggggaaataccggatgccc
tttgcctgggcacccataagcttatcaagcttcttcaatgtctccacccttgagagggag
gtaactgatgtggactctgtggttgggagaagctcagtgggtgaacggaggacattggcc
caatctagaaggctttctgaaagagccctctccttggaggaaaatggggttggatccaac
ttcaaaacctccactctgagcgttagcagctttttcaagcaggaaggagatcgccttagc
gatgaagacttattcaagtttttagctgactacaaaagatcatcatccttacagagacga
gtcaagtcaattccaggcttgctaagactggagatttctacagctccagagatcatcaat
tgctgtctgactcctgaaatgctgcccgtgaaaccctttcctgaaaaccggacacgcccg
cacaaagagattttggaatttccaacacgagaagtatatgtccctcacactgtgtacaga
aaccttctctatgtctacccacagaggctgaactttgtaaacaaactagcatcagcccgg
aacattacaataaagatccagtttatgtgtggagaagatgctagcaatgcgatgccggtc
atctttggaaaatccagcgggcctgaatttctgcaggaagtgtacacagctgttacatac
cataataagtctcctgacttttatgaagaagtgaaaattaagctccccgctaagctcaca
gtaaatcaccacctcctgttcaccttctaccatatcagctgtcagcagaagcaaggagcc
tccgtggaaactctcctgggatattcatggctgccaattctcttaaatgaacgtcttcaa
actggatcctactgtctcccagttgccttggaaaaattgccacccaactactccatgcat
tctgctgagaaagtcccattacagaatcctcccattaagtgggctgaaggacataaggga
gtatttaatattgaagtgcaagctgtttcttctgtacacacccaggacaaccacctggag
aagttcttcaccctctgccactccctggagagccaggtgaccttccccatccgcgtgctg
gatcagaaaatcagcgagatggcgctggagcatgagctgaagctcagcatcatctgcctg
aactcctcccgcctggagccgctcgtgctcttcctgcacctggtgctggacaagctcttc
cagctgtccgtgcagcccatggtcatcgctggccagacagccaacttctcccagtttgcc
ttcgagtccgtggtggccatcgccaacagtctgcacaacagcaaggacctgagcaaggac
cagcatgggaggaactgcctgctggcttcctacgtgcactacgtcttccgcctgccagag
gtgcaaagggatgtgcccaagtcaggcgctcccactgccctcctagaccctcggagctac
cacacgtatggccgcacatcagctgctgctgtgagttcaaagctgctgcaggcccgggtg
atgagcagcagtaacccagacctcgcggggacacactccgcagcagacgaggaagtgaag
aacatcatgtcttcaaagatcgccgatcgcaactgcagccgaatgtcttactattgctct
ggcagtagtgatgctccaagttcacctgcagccccaaggccagccagcaaaaagcatttc
catgaggagcttgcccttcagatggtggtcagcaccggaatggtgagagaaacagtcttc
aagtatgcctggttcttctttgagcttctggtgaaaagcatggcccagcacgtacataac
atggacaaacgggacagttttcggaggactcgtttttctgaccgtttcatggatgacata
actactattgttaatgtggtcacctcggaaattgcagcccttttagtaaaaccacagaag
gaaaatgaacaggcggaaaagatgaacatcagcctggctttcttcttgtatgaccttctc
tccctcatggatcggggctttgtgtttaacctcatcagacattattgcagccagctgtca
gccaagctcagtaaccttccaacgctcatttccatgaggctagagttcctgagaatcctc
tgtagccatgagcattacctcaatctgaaccttttttttatgaatgctgatactgctcca
acatctccttgtccttccatatcttcccagaactcaagctcctgctccagcttccaggac
cagaagatcgccagcatgttcgatctgacttccgagtaccgccagcagcacttcctcacc
gggctcctcttcacagaactggctgctgccctggatgccgaaggggaaggaatcagcaaa
gtacaaaggaaagctgtcagtgcaattcacagcctgctaagttctcacgacctggaccca
cgctgtgtcaaaccagaggtgaaggtcaaaatcgccgccctttacctacctttagttggc
atcattttggatgctttgccacagctctgtgactttacagttgcagatactcgcagatac
cgcaccagtggctcggatgaagaacaagaaggagccggtgccattaaccagaatgtggct
ctggccatagcagggaataatttcaatttgaaaacaagtggaatagtgctgtcttccttg
ccctataagcagtacaacatgctgaacgcggacactactcgcaacctcatgatctgcttc
ctctggatcatgaaaaatgctgatcagagcctcattaggaagtggattgctgacctgcca
tcaacgcagctcaacaggattttagatctacttttcatctgtgtgttatgttttgagtat
aagggaaaacagagttctgacaaagtcagtacccaagtcctgcagaagtcaagggatgtc
aaggcccggctggaagaggctttgctccgtggggaaggggccagaggggagatgatgcgc
cgccgggctccagggaacgaccgatttccaggcctaaatgaaaatttgagatggaagaaa
gagcagacacattggcggcaagctaatgagaagctagataaaacaaaggccgagttagat
caagaagccttgatcagtggcaatctggctacagaagcacatttaatcatcctggatatg
caggaaaacattatccaggcgagctcggctctggactgtaaagacagcctgctgggaggt
gttctgagggtgctggtgaattctctgaactgtgatcagagtaccacctacctgactcac
tgctttgcaacactccgtgctctcatcgccaagtttggagacttactctttgaagaggag
gtggaacagtgtttcgacctatgtcaccaagtcctgcaccactgcagcagcagcatggat
gtcacccggagccaagcctgtgccaccctttacctcctcatgaggttcagttttggagcc
accagtaattttgcaagagtaaagatgcaagtaaccatgtccctggcatctttggtggga
agagcaccagactttaatgaagagcacctgagaagatccttgaggacaattttggcctat
tcagaagaggacacagccatgcagatgactccttttcccacccaggtggaggaacttctc
tgtaatctgaatagcatcttatatgacacagtgaaaatgagggaatttcaggaagatcct
gagatgcttatggatctcatgtacagaattgccaagagttaccaggcatctcctgatctg
cggctgacctggctccagaacatggcagagaaacacaccaagaagaagtgctacacggag
gctgccatgtgcctggtgcacgccgctgcgttagtggctgagtatctgagcatgctggag
gaccacagctacctgcccgtgggcagtgtcagcttccagaatatttcttccaatgtgctg
gaggagtctgtggtctctgaggacaccctgtcacctgacgaggatggggtgtgcgcaggc
cagtacttcaccgagagtggcctggtaggcctcctggagcaggccgcggagctcttcagc
acgggaggcttatatgagacagttaatgaggtctacaagctggtcatccccatcctagaa
gcgcatcgagaattccggaagctgacactcactcacagcaagctgcagagagccttcgac
agcatcgttaacaaggatcataagagaatgtttggaacctacttccgagttggtttcttt
ggatccaaatttggggatttggatgaacaggagtttgtctacaaagagcctgcaattacc
aagcttcctgagatctcacatagactagaggcattttatggtcaatgttttggtgcagaa
tttgtggaagtgattaaagactccactcctgtggacaaaaccaagttggatcctaacaag
gcctacatacagatcacttttgtggagccctactttgatgagtatgagatgaaagacagg
gtcacatactttgagaagaatttcaacctccggaggttcatgtacaccaccccgttcacc
ctggaggggcggcctcggggagagctgcatgagcagtacagaaggaacacagtcctgacc
actatgcacgccttcccctacatcaagaccaggatcagcgtcatccagaaggaggagttt
gttttgacaccgattgaagttgccattgaagacatgaagaagaagaccctgcagttagca
gttgccattaaccaggagccgcctgatgcaaagatgcttcagatggtgctgcaaggctct
gtgggagctactgtaaatcagggaccactggaagtagcccaagtgtttttggctgaaatt
cctgctgatccaaaactctatcgacatcacaacaagttgaggttatgctttaaggaattc
atcatgagatgtggtgaagctgtagagaaaaacaagcgtctcatcacggcagaccagagg
gaatatcagcaggaactcaaaaagaactataacaagctaaaagagaacctcaggccaatg
atcgagcggaaaattccagaactgtacaagccaatattcagagttgagagtcaaaagagg
gactccttccacagatctagtttcaggaaatgtgaaacccagttgtcacagggcagctaa
蛋白序列编号: NP_982272.2
蛋白描述: dedicator of cytokinesis protein 8 isoform 1 [Homo sapiens]
蛋白大小: 2099 aa
蛋白序列:
MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVE
PVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRD
CVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPR
HLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFA
LYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKIS
ENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGD
CAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLERE
VTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLS
DEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRP
HKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPV
IFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGA
SVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKG
VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL
NSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKD
QHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARV
MSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHF
HEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDI
TTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLS
AKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQD
QKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDP
RCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVA
LAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLP
STQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMR
RRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDM
QENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEE
VEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVG
RAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDP
EMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLE
DHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFS
TGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFF
GSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNK
AYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLT
TMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGS
VGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQR
EYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS

cDNA克隆和表达质粒购买

货号 载体 片段 标签 表达系统 价格
NM203447-1 pOTB7: 全长 cDNA克隆 1000
NM203447-2 pET-28a 全长 N-His 大肠 2800
NM203447-3 pET-21b 全长 C-His 大肠 2800
NM203447-4 pET-32a 全长 N-His、N-Trx 大肠 2800
NM203447-5 pGEX-4T-1 全长 N-GST 大肠 2800
NM203447-6 pcDNA3.1(+) 全长 哺乳细胞 2800
NM203447-7 pcDNA3.1/His A 全长 N-His 哺乳细胞 2800
NM203447-8 pcDNA3.1/MycHisA 全长 C-His、C-Myc 哺乳细胞 2800
NM203447-9 pCMV-Tag 2A 全长 N-Flag 哺乳细胞 2800
NM203447-10 pCMV-Tag 4A 全长 C-Flag 哺乳细胞 2800
NM203447-11 pCMV-HA 全长 N-HA 哺乳细胞 2800
NM203447-12 pEGFP-C1 全长 N-EGFP 哺乳细胞 2800
NM203447-13 pEGFP-N1 全长 C-EGFP 哺乳细胞 2800
NM203447-14 p3xFlag-CMV-10 全长 N-3xFlag 哺乳细胞 2800
NM203447-15 p3xFlag-CMV-14 全长 C-3xflag 哺乳细胞 2800
NM203447-16 pLVX-Puro 全长 慢病毒 2800
NM203447-17 pLVX-AcGFP1-N1 全长 C-AcGFP 慢病毒 2800
NM203447-18 pLVX-AcGFP1-C1 全长 N-AcGFP 慢病毒 2800
NM203447-19 pLVX-IRES-zsGreen 全长 慢病毒 2800
NM203447-20 pFastbacI 全长 昆虫细胞 2800
NM203447-21 pFastbac-HTB 全长 N-His 昆虫细胞 2800
NM203447-22 pFastbac-CHis 全长 C-His 昆虫细胞 2800
NM203447-23 pFastbac-GST 全长 N-GST 昆虫细胞 2800

蛋白购买

基因名称 表达系统 片段 标签 产品规格 价格
DOCK8 大肠 全长 N-His 100 ug 3500
DOCK8 哺乳 全长 N-His 100 ug 5500
DOCK8 昆虫 全长 N-His 100 ug 5500

抗体购买

产品名称 品牌 价格
DOCK8抗体/ DOCK8抗体 abcam 询价
DOCK8抗体/ DOCK8抗体 CST 询价
DOCK8抗体/ DOCK8抗体 Santa Cruz 询价

 

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