SETD2基因SETD2蛋白

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基因和蛋白基本信息

基因名称: SETD2
基因又名: HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A;
Gene ID: 29072
种属 Homo sapiens
DNA序列编号: NM_014159.7
DNA描述 Homo sapiens SET domain containing 2, histone lysine methyltransferase (SETD2), transcript variant 1, mRNA
DNA大小: 8541 bp
DNA编码区:
atgaagcagctgcagccgcagccgcctccgaagatgggggatttctacgacccggagcac
ccgacccctgaagaagaagaaaatgaggcaaagattgaaaatgtgcagaaaacaggtttc
atcaaaggaccaatgttcaaaggtgttgcttctagtcgatttttgcccaaaggcaccaaa
acaaaagttaatttggaagaacagggacgacagaaggtgtcattcagcttcagccttaca
aagaaaactttgcagaataggtttctcactgcacttggcaatgaaaagcaaagtgatact
ccaaaccctccagctgtacctcttcaggtagactcgactcctaaaatgaaaatggaaatt
ggtgataccttatctactgcagaagaatcttccccaccaaagtcaagggtggaattgggc
aaaattcattttaagaaacatctgcttcatgtaacatccaggccactgctggctactacc
acagcagtagcatctccacctactcatgcagcaccattaccagcagtgatagcagaatca
acaactgtagactcaccgccctcatctccgcctccaccgcctccacctgcccaagccaca
acactctcatcaccagcaccagtaacagagccagtggccttgccacatacaccaataaca
gttctaatggcagcaccagtacccttaccagtagatgtagcagttagatctctgaaagaa
ccaccaattataattgtaccagaatctttagaagcagatactaagcaggacactatatct
aatagtttagaagaacacgtaactcaaatattgaatgagcaagcagatatttcctcaaaa
aaagaagattcccatattgggaaggatgaagaaattccagatagttctaagattagtctg
agctgtaaaaaaacaggttctaagaagaaatcctcacaatctgaaggcatctttcttggt
tcagaatctgatgaagattctgtacggacttcttcaagtcaaagatcacatgatttaaaa
ttttcagcaagcattgaaaaggaaagagattttaaaaagagctcagcacctttaaaaagt
gaggatctagggaaaccttcacgatctaaaacagacagagatgataaatattttagctat
tcaaaacttgaaagagatactcggtatgtatcttcccgatgtagatcagaaagagagcga
cggcggagcagatctcactctaggtctgagagaggctctagaactaatttatcctattcc
aggtcagaacgatctcattattatgactctgatcgtcgctaccataggagctccccttat
cgagagaggacgcgctattctcggccatacacagataacagagcacgagagagttctgac
tcagaagaagagtataagaagacatactcaaggcgtacctcatctcattcctcttcttac
agagacctaaggacatcatcctattctaaatctgatcgggactgtaaaactgagacctct
tacttagagatggaaagaagaggcaagtattcttcaaaactagaaagagaatctaaaagg
acttcagaaaatgaagcaattaaaagatgttgttctccccctaatgaactgggattccga
cgagggtcatcatattctaagcatgacagtagtgcttcccgttataaatctaccctttca
aaacctatacccaagtctgataaatttaaaaattctttctgttgtacagaattaaatgaa
gaaatcaaacagtctcattcttttagtttacagacaccttgttcaaaaggtagtgaatta
agaatgattaataaaaatcctgaaagagaaaaggctgggtctccagctccatcaaatcga
ttaaatgattcacctactttaaaaaagctagatgaattgcctatttttaagtccgaattt
ataacacatgatagccatgatagtattaaggaattagactctttatctaaagtgaagaat
gatcaattaagaagtttttgtcccatagaattaaatataaatggatctcctggggcagaa
tctgatttggcaacattttgcacttctaaaactgatgctgttttaatgacttctgatgat
agtgtgactggatcggaattatcccctttggtcaaagcatgcatgctttcatcaaatgga
tttcagaatattagtaggtgcaaagaaaaagacttggatgatacctgcatgctgcataag
aagtcagaaagcccatttagagaaacagaacctctggtgtcaccacaccaagataaactc
atgtctatgccagttatgactgtggattattccaaaacagtagttaaagaaccagttgat
acgagggtttcttgctgcaaaaccaaagattcagacatatactgtactttgaacgatagc
aacccttctttgtgtaactctgaagctgaaaatattgagccttcagttatgaagatttct
tcaaatagctttatgaatgtgcatttggaatcaaaaccagttatatgtgatagtagaaat
ttgacagatcactcaaaatttgcatgtgaagaatataagcagagcatcggtagcactagt
tcagcttctgttaatcattttgatgatttatatcaacctattgggagttcaggtattgct
tcatctcttcagagtcttccaccaggaataaaggtggacagtctaactctcttgaaatgc
ggagagaacacatctccagttctggatgcagtgctaaagagtaaaaaaagttcagagttt
ttaaagcatgcagggaaagaaacaatagtagaagtaggtagtgaccttcctgattcagga
aagggatttgcttccagggagaacaggcgtaataatgggttatctgggaaatgtttgcaa
gaggctcaagaagaagggaattccatattgcctgaaagaagaggaagaccagaaatctct
ttagatgaaagaggagaaggaggacatgtgcatacttctgatgactcagaagttgtattt
tcttcttgtgatttgaatttaaccatggaagacagtgatggtgtaacttatgcattaaag
tgtgacagtagtggtcatgccccagaaattgtgtctacagttcatgaagattattctggc
tcttctgaaagttcaaatgatgaaagtgattcagaagatacagattcggatgatagcagt
attccaagaaaccgtctccagtctgttgtggttgtgccaaagaattctactttgcccatg
gaagaaacaagtccttgttcttctcggagcagtcaaagttatagacactattctgaccat
tgggaagatgagagattggagtcaaggagacatttgtatgaggaaaaatttgaaagtata
gcaagtaaagcctgtcctcaaactgataagtttttccttcataaaggaacagagaagaat
ccggaaatttcttttacacagtccagtagaaaacaaatagataatcgcctgcctgaactt
tctcatcctcagagtgatggggttgatagtacaagtcatacagatgtgaaatctgaccct
ctgggtcacccaaattcagaggaaaccgtgaaagccaaaataccttctaggcagcaagaa
gagctgccaatttattcttctgattttgaagatgtcccaaataagtcttggcaacagacc
actttccaaaacaggccagatagtagactgggaaaaacagaattgagtttttcttcctct
tgtgagataccacatgtggatggcttgcactcatcagaagagctcagaaacttaggttgg
gacttctctcaagaaaagccttctaccacgtatcagcaacctgacagtagctatggagct
tgtggtggacacaagtatcagcaaaatgcagaacagtatggtgggacacgtgattactgg
caaggcaatggttactgggatccaagatcaggtagacctcctggaactggggttgtgtat
gatcgaactcaaggacaagtaccagattccctaacagatgatcgtgaagaagaggagaat
tgggatcaacaggatggatcccatttttcagaccagtccgataaatttcttctatccctt
cagaaagacaaggggtcagtgcaagcacctgaaataagcagcaattccattaaggacact
ttagctgtgaatgaaaagaaagatttttcaaaaaacttagaaaaaaatgatatcaaagat
agagggcctcttaaaaaaaggaggcaggaaatagagagtgattctgaaagtgatggtgag
cttcaggacagaaagaaagttagagtggaggtagagcagggagagacatcagtgccccca
ggttcagcactggttgggccctcctgtgtcatggatgacttcagggacccacagcgatgg
aaggaatgtgccaagcaagggaaaatgccatgttactttgatcttattgaagaaaatgtt
tatttaacagaaagaaagaagaataaatctcatcgagatattaagcgaatgcagtgtgag
tgtacacctctttctaaagatgaaagagctcaaggtgaaatagcatgtggggaagattgt
cttaatcgtcttctcatgattgaatgttcttctcggtgtccaaatggggattattgttcc
aatagacggtttcagagaaaacagcatgcagatgtggaagtcatactcacagaaaagaaa
ggctggggcttgagagctgccaaagaccttccttcgaacacctttgtcctagaatattgt
ggagaggtactcgatcataaagagtttaaagctcgagtgaaggagtatgcacgaaacaaa
aacatccattactatttcatggccctgaagaatgatgagataatagatgccactcaaaaa
ggaaattgctctcgtttcatgaatcacagctgtgaaccaaattgtgaaacccaaaaatgg
actgtgaacggacaactgagggttgggttttttaccaccaaactggttccttcaggctca
gagttaacgtttgactatcagttccagagatatggaaaagaagcccagaaatgtttctgc
ggatcagccaattgccggggttacctgggaggagaaaacagagtcagcatcagagcagca
ggagggaaaatgaagaaggaacgatctcgtaagaaggattcagtggatggagagctagaa
gctctgatggaaaatggtgagggtctctctgataaaaaccaggtgctcagcttatcccgg
ctaatggttagaattgaaactttggagcagaaacttacctgtctggaactcatacagaac
acacactcacagtcctgcctgaagtcctttctggaacgtcatgggctgtctttgttgtgg
atctggatggcagagctaggtgacggccgggaaagtaaccagaagcttcaggaagagatt
ataaagactttggaacacttgcccattcctactaaaaatatgttggaggaaagcaaagta
cttccaattattcaacgctggtctcagactaagactgctgtccctccgttgagtgaagga
gatgggtattctagtgagaatacatcgcgtgctcatacaccactcaacacacctgatcct
tccaccaagctgagcacagaagctgacacagacactcccaagaaactaatgtttcgcaga
ctgaaaattataagtgaaaatagcatggacagtgcaatctctgatgcaaccagtgagcta
gaaggcaaggatggcaaagaggatcttgatcaattagaaaatgtccctgtagaggaagag
gaagaattgcagtcacaacagctactcccacaacagctgcctgaatgcaaagttgatagt
gaaaccaacatagaagctagtaagctacctacatctgaaccagaagctgacgctgaaata
gagcccaaagagagcaacggcacaaaactagaagaacctattaatgaagaaacaccatcc
caagatgaagaggagggtgtgtctgatgtggagagtgaaaggagccaagaacagccagat
aaaacagtggatataagtgatttggccaccaaactcctggacagttggaaagacctaaag
gaggtatatcgaattccaaagaaaagtcaaactgaaaaggaaaacacaacaactgaacga
ggaagggatgctgttggcttcagagatcaaacacctgccccgaagactcctaataggtca
agagagagagacccagacaagcaaactcaaaataaagagaaaaggaaacgaagaagctcc
ctctcaccaccctcttctgcctatgagcggggaacaaaaaggccagatgacagatatgat
acaccaacttctaaaaagaaagtacgaattaaagaccgcaataaactttctacagaggaa
cgccggaagttgtttgagcaagaggtggctcaacgggaggctcagaaacaacagcaacag
atgcagaacctgggaatgacatcaccactgccctatgactctcttggttataatgccccg
catcatccctttgctggttacccaccaggttatcccatgcaggcctatgtggatcccagc
aaccctaatgctggaaaggtgctcctgcccacacccagcatggacccagtgtgttctcct
gctccttatgatcatgctcagcccttggtgggacattctacagaacccctttctgcccct
ccaccagtaccagtggtgccacatgtggcagctcctgtggaagtttccagttcccagtat
gtggcccagagtgatggtgtagtacaccaagactccagcgttgctgtcttgccagtgccg
gcccccggcccagttcagggacagaattatagtgtttgggattcaaaccaacagtctgtc
agtgtacagcagcagtactctcctgcacagtctcaagcaaccatatattatcaaggacag
acatgtccaacagtctatggtgtgacatcaccttattcacagacaactccaccaattgta
cagagttatgcccagccaagtcttcagtatatccaggggcaacagattttcacagctcat
ccacaaggagtggtggtacagccagccgcagcagtgactacaatagttgcaccagggcag
cctcagcccttgcagccatctgaaatggttgtgacaaataatctcttggatctgccgccc
ccctctcctcccaaaccaaaaaccattgtcttacctcccaactggaagacagctcgagat
ccagaagggaagatttattactaccatgtgatcacaaggcagactcagtgggatcctcct
acttgggaaagcccaggagatgatgccagccttgagcatgaagctgagatggacctggga
actccaacatatgatgaaaaccccatgaaggcctcgaaaaagcccaagacagcagaagca
gacacctccagtgaactagcaaagaaaagcaaagaagtattcagaaaagagatgtcccag
ttcatcgtccagtgcctgaacccttaccggaaacctgactgcaaagtgggaagaattacc
acaactgaagactttaaacatctggctcgcaagctgactcacggtgttatgaataaggag
ctgaagtactgtaagaatcctgaggacctggagtgcaatgagaatgtgaaacacaaaacc
aaggagtacattaagaagtacatgcagaagtttggggctgtttacaaacccaaagaggac
actgaattagagtga
蛋白序列编号: NP_054878.5
蛋白描述: histone-lysine N-methyltransferase SETD2 isoform 1 [Homo sapiens]
蛋白大小: 2564 aa
蛋白序列:
MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK
TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI
GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES
TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE
PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL
SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS
EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS
RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY
RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR
RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL
RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN
DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG
FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD
TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN
LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC
GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ
EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK
CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM
EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN
PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE
ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW
DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY
DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT
LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP
GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE
CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK
GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQK
GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC
GSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSR
LMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEI
IKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDP
STKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEE
EELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPS
QDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTER
GRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYD
TPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAP
HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAP
PPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSV
SVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAH
PQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARD
PEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEA
DTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKE
LKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE

cDNA克隆和表达质粒购买

货号 载体 片段 标签 表达系统 价格
NM014159-1 pOTB7: 全长 cDNA克隆 1000
NM014159-2 pET-28a 全长 N-His 大肠 2800
NM014159-3 pET-21b 全长 C-His 大肠 2800
NM014159-4 pET-32a 全长 N-His、N-Trx 大肠 2800
NM014159-5 pGEX-4T-1 全长 N-GST 大肠 2800
NM014159-6 pcDNA3.1(+) 全长 哺乳细胞 2800
NM014159-7 pcDNA3.1/His A 全长 N-His 哺乳细胞 2800
NM014159-8 pcDNA3.1/MycHisA 全长 C-His、C-Myc 哺乳细胞 2800
NM014159-9 pCMV-Tag 2A 全长 N-Flag 哺乳细胞 2800
NM014159-10 pCMV-Tag 4A 全长 C-Flag 哺乳细胞 2800
NM014159-11 pCMV-HA 全长 N-HA 哺乳细胞 2800
NM014159-12 pEGFP-C1 全长 N-EGFP 哺乳细胞 2800
NM014159-13 pEGFP-N1 全长 C-EGFP 哺乳细胞 2800
NM014159-14 p3xFlag-CMV-10 全长 N-3xFlag 哺乳细胞 2800
NM014159-15 p3xFlag-CMV-14 全长 C-3xflag 哺乳细胞 2800
NM014159-16 pLVX-Puro 全长 慢病毒 2800
NM014159-17 pLVX-AcGFP1-N1 全长 C-AcGFP 慢病毒 2800
NM014159-18 pLVX-AcGFP1-C1 全长 N-AcGFP 慢病毒 2800
NM014159-19 pLVX-IRES-zsGreen 全长 慢病毒 2800
NM014159-20 pFastbacI 全长 昆虫细胞 2800
NM014159-21 pFastbac-HTB 全长 N-His 昆虫细胞 2800
NM014159-22 pFastbac-CHis 全长 C-His 昆虫细胞 2800
NM014159-23 pFastbac-GST 全长 N-GST 昆虫细胞 2800

蛋白购买

基因名称 表达系统 片段 标签 产品规格 价格
SETD2 大肠 全长 N-His 100 ug 3500
SETD2 哺乳 全长 N-His 100 ug 5500
SETD2 昆虫 全长 N-His 100 ug 5500

抗体购买

产品名称 品牌 价格
SETD2抗体/ SETD2抗体 abcam 询价
SETD2抗体/ SETD2抗体 CST 询价
SETD2抗体/ SETD2抗体 Santa Cruz 询价

 

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