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| 出品公司: | ATCC |
|---|---|
| 菌种名称: | ATCC8688a, ATCC 8688a |
| 菌种又名: | NRRL 1369 [DSM 1906, IMI 53585, IMI 63877] |
| 菌株类型: | 坎宁安菌Cunninghamella |
| 存储人: | NRRL |
| 分离来源: | |
| 产品目录号: | 8688a |
| 其他保藏库编号: | BCRC30529,ATCC 8688a; DSM 1906; IMI 53585; IMI 63877; NRRL 1369 |
| 培养基: |
ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 307: Cornmeal agar
ATCC® Medium 336: Potato dextrose agar (PDA)
|
| 生长条件: | 24-26℃, 有氧 |
| 生物安全等级: | 1 |
| 模式菌株: | 否 |
| 应用: | 科研，生产，主要用于氧化依巴斯汀,产生1’，2’-二氢-1’，2’-二羟基鱼藤酮,产生1,2-二氢鱼藤酮,产生3’-羟基鱼藤酮,产生肌钙蛋白,生产丙咪嗪,转化生物碱,转化类黄酮,转换藤架,依巴斯汀氧化为卡巴斯汀,倍半萜内酯-科斯图内酯的转化,藤架改为藤架亚砜 |
| 菌株特点: |
坎宁安菌Cunninghamella
|
| 参考文献: |
Sariaslani FS, Rosazza JP. Microbial transformations of natural antitumor agents: Products of rotenone and dihydrorotenone transformation by Cunninghamella blakesleeana. Appl. Environ. Microbiol. 45: 616-621, 1983.
Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of flavone and isoflavone. Xenobiotica 20: 363-373, 1990. PubMed: 2346033
Mann KM, et al. Studies on microbiological oxidation of steroids by Cunninghamella blakesleeana. Effect of alcohols and phenol. Appl Microbiol 3: 14, 1955.
Schwartz H, et al. Microbial oxidation of ebastine. Appl. Microbiol. Biotechnol. 44: 731-735, 1996. PubMed: 8867630
Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940
Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.
Hufford CD, et al. Metabolism of imipramine by microorganisms. J. Pharm. Sci. 70: 151-155, 1981. PubMed: 7205217
Reighard JB, et al. Microbial biotransformations. I. O-Demethylation of 7,8-dimethoxy-2-methyl-1-(4'-methoxybenzyl) 1,2,3,4.-tetrahydroisoquinoline by Cunninghamella blakesleeana. J. Nat. Prod. 44: 466-469, 1981.
Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155
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