ATCC20864

转换宿主、β-半乳糖苷酶表达的转化宿主、表皮生长因子表达的转化宿主、醇氧化酶表达的转化宿主、表达重组百日咳博尔德氏杆菌的转化宿主、表达嗜热脂肪芽孢杆菌丙氨酸羧肽酶基因的转化宿主DACA、HIV-1包膜蛋白表达的转化宿主、Geotrichum candidum lipase A和B表达的转化宿主、表达重组人血清白蛋白的转化宿主、重组人血管抑素表达载体的改造、合成蜱抗凝血酶肽基因的转化宿主、牛肠激酶表达载体的改造、咖啡豆α-半乳糖苷酶表达的转化宿主

Nucleotide (GenBank) : KU729167 D1/D2 region of 26S rRNA gene

 

Buckholz RG. Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same. US Patent 5,268,273 dated Dec 7 1993

 

Vozza LA, et al. Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris. Bio-Technology 14: 77-81, 1996. PubMed: 9636316

 

Payne WE, et al. An inducible acid phosphatase from the yeast Pichia pastoris: characterization of the gene and its product. Gene 163: 19-26, 1995. PubMed: 7557473

 

Zhu A, et al. High-level expression and purification of coffee bean alpha- galactosidase produced in the yeast Pichia pastoris. Arch. Biochem. Biophys. 324: 65-70, 1995. PubMed: 7503561

 

Cregg JM, et al. Pichia pastoris as a host system for transformations. Mol. Cell. Biol. 5: 3376-3385, 1985. PubMed: 3915774

 

Laroche Y, et al. High-level secretion and very efficient isotopic labeling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris. Bio-Technology 12: 1119-1124, 1994. PubMed: 7765555

 

Wagner LW, et al. Use of a silicone tubing sensor to control methanol concentration during fed batch fermentation of Pichia pastoris. Biotechnol. Tech. 11: 791-795, 1997.

 

Catoni E, et al. Overexpression of lipase A and B of Geotrichum candidum in Pichia pastoris: high-level production and some properties of functional expressed lipase B. Biotechnol. Tech. 11: 689-695, 1997.

 

Fairlie WD, et al. Screening procedure for Pichia pastoris clones containing multiple copy gene inserts. BioTechniques 26: 1042-1044, 1999. PubMed: 10376135

 

Siegel RS, et al. Production of epidermal growth factor in Pichia pastoris yeast cells. US Patent 5,102,789 dated Apr 7 1992

 

de Hoop MJ, et al. Overexpression of alcohol oxidase in Pichia pastoris. FEBS Lett. 291: 299-302, 1991. PubMed: 1936277

 

Romanos MA, et al. Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: high-level production and immunological properties. Vaccine 9: 901-906, 1991. PubMed: 1811375

 

Despreaux CW, Manning RF. The dacA gene of Bacillus stearothermophilus coding for D-alanine carboxypeptidase: cloning, structure and expression in Escherichia coli and Pichia pastoris. Gene 131: 35-41, 1993. PubMed: 8370539

 

Scorer CA, et al. The intracellular production and secretion of HIV-1 envelope protein in the methylotrophic yeast Pichia pastoris. Gene 136: 111-119, 1993. PubMed: 8293993

 

Kobayashi K, et al. High-level expression of recombinant human serum albumin from the methylotrophic yeast Pichia pastoris with minimal protease production and activation. J. Biosci. Bioeng. 89: 55-61, 2000.

 

Lin J, et al. Production process for recombinant human angiostatin in Pichia pastoris. J. Ind. Microbiol. Biotechnol. 24: 31-35, 2000.

 

Liu Y, et al. Preparation of high-activity whole cell biocatalysis by permeabilization of recombinant yeasts with alcohol. J. Biosci. Bioeng. 89: 554-558, 2000.

 

De Schutter K, et al. Genome sequence of the recombinant protein production host Pichia pastoris. Nat. Biotechnol. 27: 561-566, 2009. PubMed: 19465926

 

Salamin K, et al. Secretion of an endogenous subtilisin by Pichia pastoris strains GS115 and KM71. Appl Environ Microbiol 76: 4269-4276, 2010. PubMed: 20472730

 

Prabha L, et al. Identification of the dipeptidyl aminopeptidase responsible for N-terminal clipping of recombinant Exendin-4 precursor expressed in Pichia pastoris. Protein Expr Purif 64: 155-161, 2009. PubMed: 19028585

 

Zhang X, et al. Identification and characterization of a novel yeast omega3-fatty acid desaturase acting on long-chain n-6 fatty acid substrates from Pichia pastoris. Yeast 25: 21-27, 2008. PubMed: 17914745

 

Tanneberger K, et al. A novel form of 6-phosphofructokinase. Identification and functional relevance of a third type of subunit in Pichia pastoris. J. Biol. Chem. 282: 23687-23697, 2007. PubMed: 17522059

 

Miele R, Barra D, Bonaccorsi di Patti MC. A GATA-type transcription factor regulates expression of the high-affinity iron uptake system in the methylotrophic yeast Pichia pastoris. Arch Biochem Biophys 465: 172-179, 2007. PubMed: 17592720

 

Ternes P, et al. Identification of fungal sphingolipid C9-methyltransferases by phylogenetic profiling. J Biol Chem 281: 5582-5592, 2006. PubMed: 16339149

 

Bonaccorsi di Patti MC, et al. The yeast multicopper oxidase Fet3p and the iron permease Ftr1p physically interact. Biochem Biophys Res Commun 333: 432-437, 2005. PubMed: 15946650

 

Werten MWT, de Wolf FA. Reduced proteolysis of secreted gelatin and Yps1-mediated alpha-factor leader processing in a Pichia pastoris kex2 disruptant. Appl Environ Microbiol 71(5), 2310-2317, 2005. PubMed: 15870316

 

Bhatnagar A, et al. Yeast cytochrome c is a sequence-specific DNA-binding protein. Biochem Biophys Res Commun 321: 900-904, 2004. PubMed: 15358111