| 出品公司: | ATCC | |||||||||||||||||
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| 菌种名称: | ATCC 26012 , ATCC26012 | |||||||||||||||||
| 菌种又名: | DL-1 [NRRL Y-7560] | |||||||||||||||||
| 菌株类型: | Candida parapolymorpha ,副多形假丝酵母 | |||||||||||||||||
| 存储人: | DW Levine | |||||||||||||||||
| 分离来源: | Soil, Massachusetts | |||||||||||||||||
| 产品目录号: | 26012 | |||||||||||||||||
| 其他保藏库编号: | BCRC20466，ATCC 26012 ;NRRL Y-7560 | |||||||||||||||||
| 培养基: |
ATCC®培养基28:Emmons对Sabouraud琼脂的改性，ATCC®培养基200:YM琼脂或YM肉汤，ATCC®培养基1245:Yepd
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| 生长条件: | 24-26℃, 有氧 | |||||||||||||||||
| 生物安全等级: | 1 | |||||||||||||||||
| 模式菌株: | 是 | |||||||||||||||||
| 应用: | 科研，生产，生产2-丁酮醇脱氢酶产生甲醛产过氧化氢生产异丙醇脱氢酶（NADP）二级醇脱氢酶生产甲基酮转换主机利用甲醇还原4-氯-1-（4-氟苯基）丁酮水蛭素基因表达的转化宿主 | |||||||||||||||||
| 菌株特点: | ||||||||||||||||||
| 参考文献: |
Patel RN, et al. Method for producing microbial cells and use thereof to produce oxidation products. US Patent 4,266,034 dated May 5 1981
Patel RN, et al. Microbial reduction of 1-(4-fluorophenyl)-4-[4-(5-fluoro-2-pyrimidinyl)-1-piperazinyl]butan-1-one. Biotechnol. Appl. Biochem. 17: 139-153, 1993. PubMed: 8166884
Baratti J, et al. Preparation and properties of immobilized methanol oxidase. Biotechnol. Bioeng. 20: 333-348, 1978.
Kim CH, et al. Effect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha. Biotechnol. Lett. 18: 417-422, 1996.
Cooney CL, Levine DW. Microbial utilization of methanol. Adv. Appl. Microbiol. 15: 337-365, 1972. PubMed: 4593294
Kang HA, et al. Cloning and characterization of the Hansenula polymorpha homologue of the Saccharomyces cerevisiae PMR1 gene. Yeast 14: 1233-1240, 1998. PubMed: 9791894
Kushnirov VV. Rapid and reliable protein extraction from yeast. Yeast 16: 857-860, 2000. PubMed: 10861908
Bravo M, Wang DI. Enzymatic oxidation of methanol to produce formaldehyde and hydrogen peroxide. Adv. Biotechnol. 3: 329-334, 1981.
Patel RN, et al. Oxidation of secondary alcohols to methyl ketones by yeasts. Appl. Environ. Microbiol. 38: 219-223, 1979. PubMed: 42348
Patel RN, et al. Microbial production of methyl ketones. Purification and properties of a secondary alcohol dehydrogenase from yeast. Eur. J. Biochem. 101: 401-406, 1979. PubMed: 230031
Suh SO, Zhou JJ. Methylotrophic yeasts near Ogataea (Hansenula) polymorpha: a proposal of Ogataea angusta comb. nov. and Candida parapolymorpha sp.nov. FEMS Yeast Res. 10: 631-638, 2010. PubMed: 20491937
Eldarov MA, et al. Complete sequence and analysis of the mitochondrial genome of the methylotrophic yeast Hansenula polymorpha DL-1. FEMS Yeast Res. 11(6):464-472, 2011. PubMed: 21545683.
Ravin NV, et al. Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1. BMC Genomics 14: 837, 2013. PubMed: 24279325
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