| 出品公司: | ATCC |
|---|---|
| 菌种名称: | ATCC48272, ATCC 48272 |
| 菌种又名: | C-10 |
| 菌株类型: | 顶头孢霉Acremonium chrysogenum |
| 存储人: | J Lein |
| 分离来源: | |
| 产品目录号: | 48272 |
| 其他保藏库编号: | BCRC31697，ATCC 48272 |
| 培养基: | ATCC® Medium 336: Potato dextrose agar (PDA) |
| 生长条件: | 24 ℃ |
| 生物安全等级: | 1 |
| 模式菌株: | 否 |
| 应用: | 科研，生产，主要用于产生5-（2-氨基己丙基）半胱氨酸缬氨酸合成酶ACV合成酶，产生头孢菌素C，生产脱乙酰氧基头孢菌素C合成酶，生产异青霉素N合成酶，产：18000 mcg/ml头孢菌素复合培养基 |
| 菌株特点: |
ATCC 48272是 顶头孢霉Acremonium chrysogenum 。 |
| 参考文献: |
Hollander IJ, et al. A pure enzyme catalyzing penicillin biosynthesis. Science 224: 610-612, 1984. PubMed: 6546810
Shen YQ, et al. Levels of isopenicillin N synthase and deacetoxycephalosporin C synthase in Cephalosporium acremonium producing high and low levels of cephalosporin C. Bio-Technology 4: 61-64, 1986.
Zhang J, et al. Carbon source regulation of ACV synthetase in Cephalosporium acremonium C-10. Curr. Microbiol. 18: 361-367, 1989.
Malmberg LH, Hu WS. Identification of rate-limiting steps in cephalosporin C biosynthesis in Cephalosporium acremonium: a theoretical analysis. Appl. Microbiol. Biotechnol. 38: 122-128, 1992. PubMed: 1369008
Zhang J, Demain AL. Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway of carbon sources and their metabolites. Arch. Microbiol. 158: 364-369, 1992.
Luengo JM, et al. Direct enzymatic synthesis of penicillin G using cyclases of Penicillium chrysogenum and Acremonium chrysogenum. Bio-Technology 4: 44-47, 1986.
Shen YQ, et al. Desacetoxycephalosporin C synthetase: importance of order of cofactor/reactant addition. Enzyme Microb. Technol. 6: 402-404, 1984.
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