| 出品公司: | ATCC |
|---|---|
| 菌种名称: | ATCC 6227b, ATCC6227b |
| 菌种又名: | C-25B [CBS 382.52, IFO 5781, IFO 6154, IFO 6300, IMI 57762, VKM F-401] |
| 菌株类型: | Rhizopus stolonifer，匍茎根霉菌 |
| 存储人: | AF Blakeslee |
| 产品目录号: | 6227b |
| 其他保藏库编号: | NBRC 6154=ATCC 6227b =CBS 382.52 =IFO 5781 =IFO 6300 =IMI 57762 =NRRL 12939 =VKM F-401 =NBRC 5781 =NBRC 6300 =IFO 6154 =DSM 907 |
| 培养基: | ATCC Medium 336: Potato dextrose agar (PDA) 马铃薯葡萄糖琼脂培养基（PDA培养基） |
| 生长条件: | 24℃ |
| 生物安全等级: | 1 |
| 模式菌株: | 不是 |
| 应用: | 产11α-羟化酶，产手性醇等 |
| 菌株特点: |
ATCC 6227b是Rhizopus stolonifer，匍茎根霉菌。
Nucleotide (GenBank) : Y10414 R.nigricans mRNA for stress protein.
Nucleotide (GenBank) : S50228 steroid hydroxylase cytochrome P-450 [Rhizopus nigricans, ATCC
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| 参考文献: |
Abul-Hajj YJ. Stereochemistry of C-1, 2 dehydrogenation of 5 beta-pregnane-3, 11, 20-trione by Septomyxa affinis. J. Biol. Chem. 247: 686-691, 1972. PubMed: 5058221
Zakelj-Mavric M, et al. The bioconversion of 17 alpha-ethynyl steroids with 11 alpha-hydroxylase of Rhizopus nigricans. FEMS Microbiol. Lett. 33: 117-120, 1986.
Mills JS. 10-Fluoro-19-nor steroids. US Patent 3,053,858 dated Sep 11 1962
Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971
Lanisnik T, et al. Fungal 17 beta-hydroxysteroid dehydrogenase. FEMS Microbiol. Lett. 78: 49-52, 1992. PubMed: 1334892
Breskvar K, et al. The role of cytochrome P450(11 alpha) in detoxification of steroids in the filamentous fungus Rhizopus nigricans. J. Steroid Biochem. Mol. Biol. 52: 271-275, 1995. PubMed: 7696148
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