产品名称: | 重组人干扰素-γ |
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产品又名: | IFNG细胞因子, IFNG细胞因子 |
英文名称: | Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG |
产品说明: | 我们的大肠杆菌表达系统产生了重组人干扰素γ,并表达了编码Gln24-Gln 166的靶基因。 |
背景说明: | 干扰素γ是由有丝分裂或抗原刺激淋巴细胞产生的主要干扰素。它在结构上不同于Ⅰ型干扰素,其主要活性是免疫调节。它与通常不产生Ⅱ类组织相容性抗原的细胞中的表达有关,从而导致自身免疫性疾病。γ干扰素主要由抗原、有丝分裂原或同种抗原激活的T细胞和自然杀伤细胞产生.它是由表达表面抗原CD4和CD8的淋巴细胞产生的。IL-2、FGF-碱性和表皮生长因子可诱导干扰素γ合成. |
级别: | AR |
品牌: | ELITE-MEDIA |
产品目录号: | P01579 |
产品规格: | 10ug、50ug |
产品外观: | 乳白色均一粉末。 |
制剂: | 冻干从0.2μm过滤液20 mm PB,150 mm NaCl,pH7.0。 |
保存条件: |
冻干蛋白应保存在<-20°C,室温下保存3周。
重组蛋白溶液可在4-7℃保存2~7d。
重组样品在<-20℃温度下稳定3个月。
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质量控制: |
纯度:通过减少SDS-PAGE而确定的95%以上。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
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注意事项: | 避免呼入和皮肤接触。 |
文献引用: |
Ultrasensitive aptamer fluorometric detection of IFN-γ by dual atom transfer radical polymerization amplification DongxiaoWen, et al. (Sensors and Actuators B: Chemical, 2019)
Discovery of hPRDX5based peptide inhibitors blocking PD1/PDL1 interaction through in silico proteolysis and rational design Sen Zou, et al. (Cancer Chemotherapy and Pharmacology, 2019)
Galangin ameliorates experimental autoimmune encephalomyelitis in mice via modulation of cellular immunity. Tan Kok-Tong,Li Shiming,Panny Lauren,Lin Chi-Chien,Lin Shih-Chao, J Immunotoxicol(2021Dec)
Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain. Rocha Rebeca Froes,Del Sarto Juliana L,Gomes Giovanni F,Gonçalves Mariana P,Rachid Milene A,Smetana Juliana H C,Souza Daniele G,Teixeira Mauro Martins,Marques Rafael Elias, Virulence(202112)
Effects of microplastics (MPs) and tributyltin (TBT) alone and in combination on bile acids and gut microbiota crosstalk in mice. Jiang Ping,Yuan Ge-Hui,Jiang Bao-Rong,Zhang Jing-Yi,Wang Yu-Qian,Lv Hui-Jie,Zhang Zhan,Wu Jia-Lin,Wu Qian,Li Lei, Ecotoxicol Environ Saf(2021Sep01)
Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways. Jin Rong,Hao Jiaqing,Yi Yanmei,Sauter Edward,Li Bing, Biochim Biophys Acta Mol Cell Biol Lipids(2021Aug)
Gene electrotransfer of proinflammatory chemokines CCL5 and CCL17 as a novel approach of modifying cytokine expression profile in the tumor microenvironment. Bozic T,Sersa G,Kranjc Brezar S,Cemazar M,Markelc B, Bioelectrochemistry(2021Aug)
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