产品名称: | 重组人干扰素调节因子5 |
---|---|
产品又名: | IRF5细胞因子, IRF5细胞因子 |
英文名称: | Interferon Regulatory Factor 5; IRF-5; IRF5 |
产品说明: | 重组人干扰素调节因子5由我们的大肠杆菌表达系统产生,编码MET1-Gln 498的目的基因在C-端有6His标记表达。 |
背景说明: | 干扰素调节因子5(IRF 5)是IRF家族的成员之一。它包含一个IRF色氨酸五碱基重复DNA结合结构域.IRF 5穿梭于细胞核和细胞质之间。IRF 5在磷酸化时能形成同二聚体。IRF 5作为转录因子参与干扰素、IFNA、INFB和炎症细胞因子在病毒感染中的诱导作用。IRF 5的遗传变异与10型系统性红斑狼疮的易感性有关。此外,这些遗传变异还会导致类风湿关节炎的易感性。 |
级别: | AR |
品牌: | ELITE-MEDIA |
产品目录号: | Q13568 |
产品规格: | 10ug、50ug |
产品外观: | 乳白色均一粉末。 |
制剂: | 作为0.2 mMTris-HCl,150 mMNacl,30%甘油,1 mMDTT,PH8.0的0.2μm过滤液供应。 |
保存条件: |
贮存于<-20°C,收货后稳定6个月。
请尽量减少冻融循环.
|
质量控制: |
纯度:大于80%的测定,由减少SDS-PAGE。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
|
注意事项: | 避免呼入和皮肤接触。 |
文献引用: |
miR-31 from adipose stem cell-derived extracellular vesicles promotes recovery of neurological function after ischemic stroke by inhibiting TRAF6 and IRF5. Lv, Li, Che, Exp Neurol(2021 Aug)
IRF5 Signaling in Phagocytes Is Detrimental to Neonatal Hypoxic Ischemic Encephalopathy. Al Mamun, Yu, Sharmeen, McCullough, Liu, Transl Stroke Res(2021 Aug)
Transcriptome analysis reveals a complex response to the RGNNV/SJNNV reassortant Nervous Necrosis Virus strain in sea bream larvae. Peruzza, Pascoli, Dalla Rovere, Franch, Ferraresso, Babbucci, Biasini, Abbadi, Panzarin, Toffan, Bargelloni, Fish Shellfish Immunol(2021 Jul)
HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes. Peng, Du, Son, Diamond, Proc Natl Acad Sci U S A(2021 06 29)
Oxidative stress-induced senescence mediates inflammatory and fibrotic phenotypes in fibroblasts from systemic sclerosis patients. Mancini, Acevedo, Fazez, Cuillerier, Ruiz, Huynh, Burelle, Ferbeyre, Baron, Servant, Rheumatology (Oxford)(2021 Jun 11)
|