产品名称: | 重组人IGF结合蛋白1 |
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产品又名: | IGFBP1细胞因子, PP12细胞因子 |
英文名称: | Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12 |
产品说明: | 重组人胰岛素样生长因子结合蛋白1由我们的哺乳动物表达系统产生,编码Ala26-Asn 259的靶基因在C-端有6His标记表达。 |
背景说明: | 胰岛素样生长因子结合蛋白1(IGFBP 1)由259个氨基酸(AA)编码,含有25个氨基酸残基信号肽,经加工得到234个氨基酸残基成熟蛋白。IGF结合蛋白能延长IGFS的半衰期,并能抑制或刺激IGFS对细胞生长的促进作用。它们改变IGFS与细胞表面受体的相互作用。促进细胞迁移。胰岛素样生长因子结合蛋白(IGFBP)对胰岛素样生长因子(IGF)转运和摄取的调节。 |
级别: | AR |
品牌: | ELITE-MEDIA |
产品目录号: | P08833 |
产品规格: | 10ug、50ug |
产品外观: | 乳白色均一粉末。 |
制剂: | 冻干从0.2μm过滤的PBS溶液中,pH值为7.4。 |
保存条件: |
冻干蛋白应保存在<-20°C,室温下保存3周。
重组蛋白溶液可在4-7℃保存2~7d。
重组样品在<-20℃温度下稳定3个月。
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质量控制: |
纯度:通过减少SDS-PAGE而确定的95%以上。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
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注意事项: | 避免呼入和皮肤接触。 |
文献引用: |
Hormonal stress responses of growth hormone and insulin-like growth factor-I in highly resistance trained women and men. Hatfield, Kraemer, Volek, Nindl, Caldwell, Vingren, Newton, Häkkinen, Lee, Maresh, Hymer, Growth Horm IGF Res(2021 Aug)
Effects of fasting and re-feeding on the expression of CCK, PYY, hypothalamic neuropeptides, and IGF-related genes in layer and broiler chicks. Kewan, Saneyasu, Kamisoyama, Honda, Comp Biochem Physiol A Mol Integr Physiol(2021 Jul)
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes. Lay, Hale, Stowell-Connolly, Pope, Nair, Ju, Marquez, Rollason, Hurcombe, Hayes, Roberts, Gillam, Allington, Nelson, Kretzler, Holly, Perks, McArdle, Welsh, Coward, Diabetologia(2021 Jul)
Role of physical exercise in modulating the insulin-like growth factor system for improving breast cancer outcomes: A meta-analysis. Han, Kim, Exp Gerontol(2021 Jun 18)
Acute Effect of Popular High-Intensity Functional Training Exercise on Physiologic Markers of Growth. Kliszczewicz, Markert, Bechke, Williamson, Clemons, Snarr, McKenzie, J Strength Cond Res(2021 Jun 01)
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