产品名称: | 重组人死亡受体3 |
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产品又名: | TNFRSF25细胞因子, TNFRSF25细胞因子 |
英文名称: | Tumor necrosis factor receptor superfamily member 25;APO3; DDR3; DR3; TNFRSF12; WSL; WSL1;TNFRSF25;Protein WSL-1;LARD;Protein WSL;Lymphocyte-associated receptor of death;Death receptor 3;Apoptosis-mediating receptor TRAMP;Apoptosis-inducing receptor AIR;Ap |
产品说明: | 重组人死亡受体3由我们的哺乳动物表达系统产生,编码Gln25-Phe201的目的基因在C-端有一个FC标记表达。 |
背景说明: | 肿瘤坏死因子受体超家族成员25(TNFRSF 25)包含1个死亡域和4个TNFR-Cys重复序列.TNFRSF 25是肿瘤坏死因子受体超家族的一种细胞表面受体,介导凋亡信号和分化,由一夫一配体TL1A(TNFSF 15)激活,TNFRSF 15在抗原提呈细胞和某些内皮细胞中迅速表达,而Toll样受体或FC受体激活后,TNFRSF 25被激活。这种受体可以通过Tradd适配器分子刺激NF-kappa B活性,也可以通过FADD适配器分子刺激caspase活化和调节细胞凋亡。它可能在调节淋巴细胞的动态平衡方面发挥作用。 |
级别: | AR |
品牌: | ELITE-MEDIA |
产品目录号: | Q93038 |
产品规格: | 10ug、50ug |
产品外观: | 乳白色均一粉末。 |
制剂: | 冻干从0.2μm过滤的PBS溶液中,pH值为7.4。 |
保存条件: |
冻干蛋白应保存在<-20°C,室温下保存3周。
重组蛋白溶液可在4-7℃保存2~7d。
重组样品在<-20℃温度下稳定3个月。
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质量控制: |
纯度:通过减少SDS-PAGE而确定的95%以上。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
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注意事项: | 避免呼入和皮肤接触。 |
文献引用: |
Analysis of therapeutic potential of preclinical models based on DR3/TL1A pathway modulation (Review). Yu, Jiang, Sun, Su, Lin, Exp Ther Med(2021 Jul)
The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes. Zhao, Papadopoulos, Lybrand, Moustakas, Bondinas, Carlsson, Larsson, Ludvigsson, Marcus, Persson, Samuelsson, Wang, Pyo, Nelson, Geraghty, Rich, Lernmark, BDD study group, EBioMedicine(2021 Jun 18)
Frequency, clinical features, inflammatory cytokines and genetic background of latent autoimmune diabetes in youth in youth-onset type 2 diabetes: Results from a nationwide, multicentre, clinic-based, cross-sectional study (LADA China). Xiang, Liu, Yun, Zhou, Li, Luo, Xie, Che, Lin, Yang, Li, Huang, Xu, Zhou, Diabetes Obes Metab(2021 Jun)
Low-Risk Human Leukocyte Antigen Genes and Mild Villous Atrophy Typify Celiac Disease With Immunoglobulin A Deficiency. Schirru, Jores, Rossino, Corpino, Cucca, Congia, J Pediatr Gastroenterol Nutr(2021 Jun 01)
Thyrotropin Receptor-Specific Lymphocytes in Adenovirus-TSHR-Immunized Native and Human Leukocyte Antigen-DR3-Transgenic Mice and in Graves' Disease Patient Blood. Degen, Gavvovidis, Blankenstein, Uhland, Ungerer, Thyroid(2021 Jun)
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