VEGF165细胞因子

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规格: 10ug 50ug

联系方式:I47-825O-882O

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VEGF165细胞因子产品基本信息

产品名称: 重组人VEGF-A
产品又名: IVEGF165细胞因子, IVEGF165细胞因子
英文名称: Vascular Endothelial Growth Factor Isoform 165; VEGF165
产品说明: 重组人血管内皮生长因子A是由我们的哺乳动物表达系统和目标基因Ala27-Arg 191表达。
背景说明: 人血管内皮生长因子(VEGF)又称血管内皮生长因子(VEGF-A)和血管通透性因子(VPF),属于半胱氨酸结生长因子中血小板源性生长因子家族。无论在生理上还是在病理上,它都是一种强有力的血管生成和血管生成的激活剂。VEGF-A有8种不同的剪接异构体,其中VEGF 165是最丰富的。VEGF 165是由两个糖基化的165氨基酸多肽链组成的二硫键同二聚体。VEGF通过与细胞表面的酪氨酸激酶受体VEGFR 1和VEGFR 2结合来刺激细胞的反应。人们普遍认为,VEGFR 2介导了几乎所有已知的细胞对VEGF的反应,而VEGFR 1的功能被认为是调控VEGFR 2信号的功能。
级别: AR
品牌: ELITE-MEDIA
产品目录号: P15692-4
产品规格: 10ug、50ug
产品外观: 乳白色均一粉末。
制剂: 冻干从0.2μm过滤液20 mm PB,150 mm NaCl,pH 7.2。
保存条件:
冻干蛋白应保存在<-20°C,室温下保存3周。
重组蛋白溶液可在4-7℃保存2~7d。
重组样品在<-20℃温度下稳定3个月。
 质量控制:
纯度:通过减少SDS-PAGE而确定的95%以上。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
注意事项: 避免呼入和皮肤接触。
文献引用:
Engineered stem cell mimics to enhance stroke recovery Paul M.George, et al. (Biomaterials, 2018)
Over expressing miR-19b-1 suppress breast cancer growth by inhibiting tumor microenvironment induced angiogenesis Runting Yin , et al. (The International Journal of Biochemistry & Cell Biology, 2018)
Efficacy of Lenvatinib, a multitargeted tyrosine kinase inhibitor, on laser-induced CNV mouse model of neovascular AMD Xian Wei, et al. (Experimental Eye Research, 2017)
IBI302, a Promising Candidate for AMD Treatment, Targeting Both the VEGF and Complement System with High Binding Affinity in vit Ren X, et al. (Experimental eye research, 2016)
Investigation of the mechanisms of VEGF-mediated compensatory lung growth: the role of the VEGF heparin-binding domain. Yu, Ko, Dao, Secor, Pan, Cho, Mitchell, Kishikawa, Bielenberg, Puder, Sci Rep(2021 Jun 04) 
Use of NanoBiT and NanoBRET to monitor fluorescent VEGF-A binding kinetics to VEGFR2/NRP1 heteromeric complexes in living cells. Peach, Kilpatrick, Woolard, Hill, Br J Pharmacol(2021 Jun) 
Porphyrin-based covalent organic framework as bioplatfrom for detection of vascular endothelial growth factor 165 through fluorescence resonance energy transfer. Cui, Kan, Li, Yang, Wang, He, Lou, Xue, Zhang, Talanta(2021 Jun 01) 
VEGF165 gene-modified human umbilical cord blood mesenchymal stem cells protect against acute liver failure in rats. Chen, Tang, Liao, Liu, Lin, J Gene Med(2021 May 31) 
Determination of VEGF165 using impedimetric aptasensor based on cyclohexanehexone-melem covalent-organic framework. Li, Liu, Wang, Jia, Zhang, Huang, Zhou, Zhang, Mikrochim Acta(2021 May 28) 

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