产品名称: | 重组人C-C基序化学因子27 |
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产品又名: | SCYA27细胞因子, SCYA27细胞因子 |
英文名称: | C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; Eskine; IL-11 R-Alpha-Locus Chemokine; Skinkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27 |
产品说明: | 用大肠杆菌表达系统构建了重组人C-C基序-Chemokine 27基因,并表达了编码Phe25-G 112的目的基因。 |
背景说明: | 人趋化因子(C-C motif)配体27(CCL 27)是CC趋化因子家族中的一种小细胞因子,在性腺、胸腺、胎盘和皮肤等多种组织中均有表达。CCL 27通过与趋化因子受体CCR 10结合而发挥趋化作用。CCL 27主要表达于皮肤,与T细胞介导的皮肤炎症有关。人与小鼠CCL 27具有84%的成熟序列同源性。 |
级别: | AR |
品牌: | ELITE-MEDIA |
产品目录号: | Q9Y4X3 |
产品规格: | 10ug、50ug |
产品外观: | 乳白色均一粉末。 |
制剂: | 冻干从0.2μm过滤液20 mm PB,500 mm NaCl,pH7.5。 |
保存条件: |
冻干蛋白应保存在<-20°C,室温下保存3周。
重组蛋白溶液可在4-7℃保存2~7d。
重组样品在<-20℃温度下稳定3个月。
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质量控制: |
纯度:通过减少SDS-PAGE而确定的95%以上。
内毒素:LAL法测定小于0.1ng/g(1 Eu/?g)。
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注意事项: | 避免呼入和皮肤接触。 |
文献引用: |
Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets. Kim, Lee, Kim, Kameyama, Nazarian, Der, Cohen, Guttman-Yassky, Putterman, Krueger, J Allergy Clin Immunol(2021 Apr 29)
Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10. Lim, Lane, Canals, Stone, Int J Mol Sci(2021 Apr 19)
Biomarkers in atopic dermatitis-a review on behalf of the International Eczema Council. Renert-Yuval, Thyssen, Bissonnette, Bieber, Kabashima, Hijnen, Guttman-Yassky, J Allergy Clin Immunol(2021 Apr)
Oral Administration of Live and Dead Cells of Lactobacillus sakei proBio65 Alleviated Atopic Dermatitis in Children and Adolescents: a Randomized, Double-Blind, and Placebo-Controlled Study. Rather, Kim, Lew, Cha, Lee, Nam, Majumder, Lim, Lim, Seo, Park, Probiotics Antimicrob Proteins(2021 Apr)
Immunoinflammatory Biomarkers in Serum Are Associated with Disease Severity in Atopic Dermatitis. Holm, Hurault, Agner, Clausen, Kezic, Tanaka, Thomsen, Dermatology(2021 Mar 17)
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